NDLI: Nanotool exchanger system based on E-SEM nanorobotic manipulation system

Content Provider	IEEE Xplore Digital Library
Author	Nakajima, M. Kawamoto, T. Hirano, T. Kojima, M. Fukuda, T.
Copyright Year	2012
Description	Author affiliation: Department of Micro-Nano Systems Engineering of Nagoya University, Furo-cho, Chikusa-ku, 464-8603, Japan (Kawamoto, T.; Kojima, M.; Fukuda, T.) \|\| Center For Micro-nano Mechatronics of Nagoya University, Furo-cho, Chikusa-ku, 464-8603, Japan (Nakajima, M.; Hirano, T.)
Abstract	A novel nanotool exchanger system is proposed based on Environmental Scanning Electron Microscope (E-SEM) nanorobotic manipulation system. We proposed to use the E-SEM nanomanipulation system for the analysis of biological specimen using various “nanotools” to realize flexible and complex nano-scale stiffness measurement, adhesion force measurement, cutting, and injection. The E-SEM can use to observe the biological samples in nano-scale and real-time without any drying or dyeing processes. As previous works, we applied the system to manipulate biological specimens, such as Caenorhabditis elegans (C. elegans) and yeast cells. To maintain the livable condition of biological cells, it is important to reduce the exchange time of the nanotools. This is also important to improve the efficiency of biological specimen analysis using various nanotools without break the chamber pressure. This paper presents a novel nanotool exchanger system for exchanging different nanotools within the ESEM chamber. Through the nanotool exchanger system, the following advantages are mainly obtained, 1) it is not needed to open the sample chamber to exchange the nanotools and to evacuate the sample chamber pressure again, 2) it is not needed to operate manually to exchange nanotools, 3) it is possible to recover the nanotools by exchanging new one, 4) it is possible to use different tools continuously. Firstly, the design and fabrication are presented for the proposed nanotool adaptor, nanotool attachment and nanotool holder. Finally, we demonstrate to exchange the different nanotools based on E-SEM nanomanipulation system.
Starting Page	2773
Ending Page	2778
File Size	610138
Page Count	6
File Format	PDF
ISBN	9781467314039
ISSN	10504729
e-ISBN	9781467314053
e-ISBN	9781467314046
DOI	10.1109/ICRA.2012.6225333
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-05-14
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Nanobioscience Scanning electron microscopy Indium Force measurement
Content Type	Text
Resource Type	Article
Subject	Artificial Intelligence Control and Systems Engineering Electrical and Electronic Engineering Software

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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