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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Heida, T. Rutten, W.L.C. Marani, E. |
| Copyright Year | 2001 |
| Description | Author affiliation: Fac. of Electr. Eng., Twente Univ., Enschede, Netherlands (Heida, T.; Rutten, W.L.C.; Marani, E.) |
| Abstract | Cortical rat neurons were trapped by negative dielectrophoresis (DEP) using a planar quadrupole electrode structure. The non-uniform field created by this structure was calculated using a finite element software package. By representing the neuron by a single-shell model the membrane potential induced by the electric field can be estimated. It was investigated whether the physiological state of the trapped neurons can be predicted using this estimation. Experimentally, the physiological state of cortical cells trapped at different amplitudes and frequencies of the input signal was determined using a staining method. The conclusion is that a rough estimate of the minimum frequency and maximum amplitude can be given in order to predict the status of viability of the cells after being dielectrophoretically trapped. |
| Starting Page | 753 |
| Ending Page | 756 |
| File Size | 392837 |
| Page Count | 4 |
| File Format | |
| ISBN | 0780372115 |
| ISSN | 1094687X |
| DOI | 10.1109/IEMBS.2001.1019050 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2001-10-25 |
| Publisher Place | Turkey |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Nonuniform electric fields Neurons Dielectrophoresis Frequency estimation Electrodes Finite element methods Software packages Biomembranes State estimation Amplitude estimation |
| Content Type | Text |
| Resource Type | Article |
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