NDLI: Dense electrical map reconstruction from ECG/MCG measurements using a priori myocardial fiber structure and activation sequence information

Content Provider	IEEE Xplore Digital Library
Author	Debreuve, E. Gullberg, G.T.
Copyright Year	2001
Description	Author affiliation: Dept. of Radiol., Utah Univ., Salt Lake City, UT, USA (Debreuve, E.; Gullberg, G.T.)
Abstract	Reconstruction of the current density in the myocardium from electrocardiography and magnetocardiography (ECG/MCG) measurements is an ill-posed inverse problem. If the current dipole model is used, 6 parameters must be determined per dipole: 3 for the dipole position, 3 for the dipole moment. Considering the small number of measurements it is not realistic to properly reconstruct a dense dipole field. A priori information is required. Our goal is to reconstruct a dense dipole field within a voxelized image of the heart at a particular instant of the cardiac cycle. A dipole is assigned to each voxel (therefore the position is known) and its orientation is given by the local muscle fiber direction eventually observed on an MR diffusion image of the heart. Only the dipole moment magnitude has to be determined. We constrain this simplified inverse problem using the knowledge of a standard activation sequence of the myocardium, thereby encouraging significant magnitudes in regions where the muscle is supposed to be activated at that time and discouraging non-zero magnitudes in other regions. This constraint is implemented using semi-quadratic regularization. The minimization of the regularized criterion is performed using a conjugate gradient algorithm. Preliminary results are provided using a homogeneous sphere.
Starting Page	315
Ending Page	318
File Size	325565
Page Count	4
File Format	PDF
ISBN	0780372115
ISSN	1094687X
DOI	10.1109/IEMBS.2001.1018923
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2001-10-25
Publisher Place	Turkey
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Electrocardiography Electric variables measurement Myocardium Image reconstruction Magnetic field measurement Inverse problems Heart Muscles Current density Magnetic moments
Content Type	Text
Resource Type	Article

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