NDLI: Estimation of total baroreflex gain using an equilibrium diagram between sympathetic nerve activity and arterial pressure

Content Provider	IEEE Xplore Digital Library
Author	Kawada, T. Sugimachi, M. Sunagawa, K.
Copyright Year	2001
Abstract	The arterial baroreflex system may be divided into the mechano-neural arc from pressure input to sympathetic nerve activity (SNA) and the neuro-mechanical arc from SNA to arterial pressure (AP). We explored a new strategy to estimate total baroreflex gain (G/sub baro/) using an equilibrium diagram between the mechano-neural and neuro-mechanical arcs. In 8 anesthetized rabbits, a neck suction procedure (NS) was simulated by shifting isolated carotid sinus pressure above AP by 30 mmHg. NS shifted the mechano-neural arc alone, yielding the slope of the neuro-mechanical arc around the operating point. A lower body negative pressure procedure (LBNP) was simulated by 5 ml/kg hemorrhage. LBNP shifted the neuro-mechanical arc alone, yielding the slope of the mechano-neural arc around the operating point. By multiplying the slopes of the neuro-mechanical and mechano-neural arcs, we obtained G/sub baro/ under baroreflex closed-loop conditions. We also estimated G/sub baro/ from the relationship between isolated carotid sinus pressure and AP under baroreflex open-loop conditions. G.. estimated by the equilibrium diagram matched reasonably well with that estimated by the open-loop method (y=1.06/spl times/-0.09, r/sup 2/=0.96, SEE=0.15). In conclusion, G/sub baro/ could be estimated using the equilibrium diagram without opening the baroreflex negative feedback loop when data obtained from NS and LBNP were combined in a given subject.
Starting Page	574
Ending Page	577
File Size	269905
Page Count	4
File Format	PDF
ISBN	0780372115
ISSN	1094687X
DOI	10.1109/IEMBS.2001.1018998
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2001-10-25
Publisher Place	Turkey
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Baroreflex Space technology Blood pressure Pharmaceutical technology Cardiology Neck Negative feedback loops Isolation technology Negative feedback Attenuation
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in