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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Arts, T. van der Toorn, A. Barenbrug, P. Snoep, G. Maessen, J. |
| Copyright Year | 2001 |
| Description | Author affiliation: Cardiovascular Res. Inst., Maastricht Univ., Netherlands (Arts, T.; van der Toorn, A.) |
| Abstract | Many cardiac diseases cause transmural differences in myofiber function. With the Magnetic Resonance Imaging Tagging technique a grid of magnetic tags was attached to the heart. Using a model of cardiac mechanics the motion of these tags was analyzed to deduct the transmural gradient or myofiber shortening. In normal, young healthy subjects (n=9), the transmural difference in myofiber shortening varies little, about /spl plusmn/4% (sd) of mean shortening. In patients with aortic stenosis subendocardial function is at risk. In a group of such patients (n=5) fiber shortening in the subendocardial layers was found to be decreased by 23/spl plusmn/20% relative to the subepicardial layers. This finding indicates that a model of cardiac mechanics can be used as a tool to convert MRI-tagging motion data to clinically useful information on a transmural gradient in contractile function. Presently, no other methods are available to detect such transmural gradient noninvasively. |
| Starting Page | 95 |
| Ending Page | 97 |
| File Size | 262109 |
| Page Count | 3 |
| File Format | |
| ISBN | 0780372115 |
| ISSN | 1094687X |
| DOI | 10.1109/IEMBS.2001.1018855 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2001-10-25 |
| Publisher Place | Turkey |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Myocardium Magnetic resonance imaging Tagging Heart Cardiac disease Magnetic analysis Image sequence analysis Art Cardiology Surgery |
| Content Type | Text |
| Resource Type | Article |
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