NDLI: Noninvasive imaging of ventricular activation - application to patients with WPW-syndrome

Content Provider	IEEE Xplore Digital Library
Author	Fischer, G. Tilg, B. Modre, R. Roithinger, F.X. Hintringer, F. Berger, T. Abou-Harb, M. Hanser, F. Messnarz, B. Schocke, M.F.H. Kremser, C. Pachinger, O. Wach, P.
Copyright Year	2001
Description	Author affiliation: Inst. of Biomed. Eng., Graz Univ. of Technol., Austria (Fischer, G.; Tilg, B.; Modre, R.)
Abstract	Noninvasive activation time (AT) imaging using electrocardiographic (ECG) mapping data provides information about electrical propagation through the heart with a high spatio-temporal resolution. This study presents an attempt to clinically validate AT imaging in two patients with WPW-syndrome. We acquired 62-channel ECG mapping data during treatment in the catheter laboratory. The individual torso geometry was obtained by magnetic resonance imaging. Based on this data the AT map was estimated for the entire ventricular surface off-line for validation purposes. The AT maps were computed for a pacing protocol in the region of the right ventricular apex and for sinus rhythm beats prior and after successful pathway ablation. For paced beats the first onset activation was always found to be located in the apical region of the right ventricular endocardium. For beats in sinus rhythm prior to pathway ablation the location of the first onset of activation matched with the anatomic position of the ablation catheter during successful ablation. After the treatment this spot of early basal activation disappeared in the computed AT maps. Thus, we conclude that noninvasive AT imaging from ECG mapping data presents a novel clinical tool for assessment of cardiac electrical activation In reference to the associated anatomy.
Starting Page	311
Ending Page	314
File Size	390994
Page Count	4
File Format	PDF
ISBN	0780372115
ISSN	1094687X
DOI	10.1109/IEMBS.2001.1018922
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2001-10-25
Publisher Place	Turkey
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	High-resolution imaging Electrocardiography Magnetic resonance imaging Catheters Rhythm Heart Image resolution Laboratories Torso Geometry
Content Type	Text
Resource Type	Article

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