NDLI: Micro-photodiode arrays as artificial retina implant: electrical properties

Content Provider	IEEE Xplore Digital Library
Author	Stelzle, M. Stett, A. Brunner, B. Graf, M. Nisch, W.
Copyright Year	2000
Description	Author affiliation: Natural & Med. Sci. Inst., Reutlingen, Germany (Stelzle, M.)
Abstract	Micro-photodiode arrays have been developed and are intended to serve as a replacement for degenerated photoreceptor cells in the retina. The chips are implanted into the sub-retinal space. Electric current generated in tiny micro-photodiodes is delivered to the neuronal network in the retina via micro-electrodes. Since the coupling between electrode and tissue is capacitive of nature, only transient signals may be used for stimulation. Accordingly, a high capacitance of the interface between electrodes and tissue is an important prerequisite for efficient charge transfer. In addition, the electric properties of the micro-photodiodes as are reflected in current/voltage traces have a profound influence on the overall charge delivery. Therefore, the entire system made up of micro-photodiode array, electrode/electrolyte interface and tissue has to be taken into consideration. Current delivery has been both calculated and measured based on current/voltage traces and electrode capacitance data. The authors' results indicate charged balanced operation of the device and a non-zero electrode polarization. The latter may be avoided, if an active current sink is employed in order to draw backward current.
Starting Page	419
Ending Page	422
File Size	348467
Page Count	4
File Format	PDF
ISBN	0780364651
ISSN	1094687X
DOI	10.1109/IEMBS.2000.900764
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2000-07-23
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Retina Implants Electrodes Voltage Photoreceptors Biological neural networks Charge transfer Capacitance measurement Current measurement Polarization
Content Type	Text
Resource Type	Article

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