NDLI: A solid-state intraoperative probe system

Content Provider	IEEE Xplore Digital Library
Author	Raylman, R.R.
Copyright Year	2000
Description	Author affiliation: Dept. of Radiol., West Virginia Univ., Morgantown, WV, USA (Raylman, R.R.)
Abstract	Intraoperative beta probes must be capable of detecting relatively small amounts of radionuclide in an environment where a significant photon background exists. The probe system in this investigation consisted of two stacked ion-implanted-silicon detectors. The rear detector served as a photon monitor, whose data and very good beta detection capabilities was used to correct for photon contamination present in the front detector's readings. Miniaturized electronics for the operation of the detectors were housed in the handle of the probe wand. The amplified signals from these electronics were sent to a power and processing module where the pulses were pulse-height discriminated. This unit also housed the rechargeable lead-acid batteries used to power the system. The two channels of TTL pulse data created by the discriminators were input to a laptop computer where the they were processed and displayed. Beta and photon detection sensitivities were measured using Fluorine-18 (positron emitter) and Indium-111 (conversion electron emitter). The probe was found to have a positron detection sensitivity (Fluorine-18) of 7.21/spl plusmn/0.11 cps/nCi and a 0.0004/spl plusmn/0.0389 cps/nCi photon detection sensitivity. The measured electron detection sensitivity (Indium-111) was 1.42/spl plusmn/0.04 cps/nCi, detected photon sensitivity was 0.0034/spl plusmn/0.020 cps/nCi. The very good beta sensitivity and low photon sensitivity indicate that this system may be a useful aid for performing radionuclide-guided cancer surgeries using either positron or electron-emitting radiopharmaceuticals.
Starting Page	344
Ending Page	350
File Size	756973
Page Count	7
File Format	PDF
ISBN	0780364651
ISSN	1094687X
DOI	10.1109/IEMBS.2000.900745
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2000-07-23
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Solid state circuits Probes Detectors Pulse amplifiers Positrons Batteries Pollution measurement Monitoring Contamination Signal processing
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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