NDLI: An iterative transmission algorithm incorporating cross-talk correction for SPECT

Content Provider	IEEE Xplore Digital Library
Author	Narayanan, M.V. King, M.A. Byrne, C.L.
Copyright Year	2000
Description	Author affiliation: Massachusetts Univ. Med. Sch., Worcester, MA, USA (Narayanan, M.V.)
Abstract	Simultaneous emission/transmission acquisitions in cardiac SPECT with a Tc/Gd source combination offer the capability for non-uniform attenuation correction. However, cross-talk of Tc-99m photons down-scattered into the Gd-153 energy window contaminates the reconstructed transmission map used for attenuation correction. The estimated cross-talk contribution can be removed prior to transmission reconstruction or incorporated in the reconstruction algorithm itself. Here, the authors propose an iterative transmission algorithm (MLTG-S) based on the maximum-likelihood gradient algorithm (MLTG) that explicitly accounts for this cross-talk estimate. Clinical images were acquired on a three-headed SPECT camera, acquiring Tc-99m emission and Gd-153 transmission images simultaneously. Subtracting the cross-talk estimate prior to transmission reconstruction with MLTG causes the number of zeros to increase in the corrected projections due to increased attenuator size or enhanced cross-talk. This results in inaccurate attenuation coefficients. MLTG-S reconstructions on the other hand, yield better estimates of attenuation maps, by avoiding the subtraction of the cross-talk estimate. Comparison of emission slices corrected for nonuniform attenuation also reveal that inaccuracies in the reconstructed attenuation map can artificially enhance the extracardiac activity, confounding one's ability to visualize the left-ventricular walls.
Starting Page	361
Ending Page	363
File Size	280409
Page Count	3
File Format	PDF
ISBN	0780364651
ISSN	1094687X
DOI	10.1109/IEMBS.2000.900749
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2000-07-23
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Iterative algorithms Attenuation Image reconstruction Yield estimation Single photon emission computed tomography Reconstruction algorithms Maximum likelihood estimation Cameras Attenuators Visualization
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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