NDLI: Reliability-aware synthesis for flow-based microfluidic biochips by dynamic-device mapping

Content Provider	IEEE Xplore Digital Library
Author	Tsun-Ming Tseng Bing Li Tsung-Yi Ho Schlichtmann, U.
Copyright Year	2015
Description	Author affiliation: Dept. of Comput. Sci., Nat. Chiao Tung Univ., Hsinchu, Taiwan (Tsung-Yi Ho) \|\| Inst. for Electron. Design Autom., Tech. Univ. Munchen, Munich, Germany (Tsun-Ming Tseng; Bing Li; Schlichtmann, U.)
Abstract	On flow-based biochips, valves that are used to form peristaltic pumps wear out much earlier than valves for transportation since the former are actuated more often, which leads to a reduced lifetime of the chip. In this paper, we introduce a valve-role-changing concept to avoid always using the same valves for peristalsis. Based on this, we generate dynamic devices from a valve-centered architecture to distribute the valve actuation activities evenly and reduce the largest number of valve actuations with even fewer valves. In addition, we propose in situ on-chip storages, which can overlap with other devices, so that less area is needed compared with dedicated storages on traditional chips. Moreover, our method provides good support for assays requiring different volumes and ratios of samples. Experiments show that compared with traditional designs, the largest number of valve actuations can be reduced by 72.97% averagely, while the number of valves is reduced by 10.62%.
Starting Page	1
Ending Page	6
File Size	1045543
Page Count	6
File Format	PDF
ISBN	9781479980529
DOI	10.1145/2744769.2744899
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-06-08
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Association for Computing Machinery, Inc. (ACM)
Subject Keyword	Reliability Valves Heuristic algorithms Routing Mixers Indexes
Content Type	Text
Resource Type	Article

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