NDLI: Image Based CFD Modeling of Coronary Artery Wall Shear Stress and Importance of Patient-Specific Velocity Boundary Conditions

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Kevin, R. Johnson John, N. Oshinski
Copyright Year	2007
Abstract	Low and oscillatory arterial wall shear stress (WSS) have been shown to have an effect on many factors implicated in atherosclerotic lesion development. The majority of studies on the relationship between low or oscillating WSS and sites of intimal thickening and early atherosclerotic lesion development are based on in-vitro model studies of flow and WSS distribution. These models are based on average vessel geometries with average flow conditions and compared to average pathology distribution of lesions that may obscure the true relationship between WSS and lesion distribution[1]. Recent techniques have been developed using coronary MR angiography to create patient-specific 3D models along with velocity measurements of blood flow using phase contrast magnetic resonance (PCMR). However, these models may lack adequate spatial resolution for accurate, localized calculation of WSS[2]. Current, state-of-art multidetector CT scanners offer improvements in spatial resolution over MRI for creation of 3D vessel models.
Sponsorship	Bioengineering Division
Starting Page	555
Ending Page	556
Page Count	2
File Format	PDF
ISBN	0791847985
DOI	10.1115/SBC2007-176224
Conference Proceedings	ASME 2007 Summer Bioengineering Conference
Language	English
Publisher Date	2007-06-20
Publisher Place	Keystone, Colorado, USA
Access Restriction	Subscribed
Subject Keyword	Computational fluid dynamics Three-dimensional models Vessels Magnetic resonance Modeling Flow (dynamics) Blood flow Magnetic resonance imaging Atherosclerosis Shear stress Boundary-value problems Resolution (optics) Velocity measurement Coronary arteries
Content Type	Text
Resource Type	Article

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