NDLI: Biomechanical Effect of Lumbar Disc Degeneration Under Flexion/Extension: A Finite Element Model Study

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Ruberté, Lissette M. Natarajan, Raghu Gunnar, B. J. Andersson
Copyright Year	2007
Abstract	Degenerative disc disease (DDD) is a progressive pathological condition observed in 60 to 80% of the population [1]. It involves changes in both the biochemistry and morphology of the intervertebral disc and is associated with chronic low back pain, sciatica and adult scoliosis [2,3]. The most accepted theory of the effects of DDD on the kinematics of the spine is that proposed by Kirkaldy-Willis and Farfan which states that the condition initiates as a temporary dysfunction, followed by instability and then re-stabilization as the disease progresses [4]. Although there is no clear relationship between disc degeneration and the mechanical behavior of the lumbar spine, abnormal motion patterns either in the form of increased motion or erratic motion have been reported from studies on human cadaveric motion segments [5,6]. To date however no study has looked at how disc degeneration affects the adjacent segment mechanics. IN vivo testing is difficult for these purposes given that specimens are generally obtained from people at the later stages of life and consequently often display multiple pathologies. A finite element model is a viable alternative to study the mechanics of the segments adjacent to the diseased disc. It is hypothesized that moderate degeneration at one level will alter the kinematics of the whole lumbar spine.
Sponsorship	Bioengineering Division
Starting Page	355
Ending Page	356
Page Count	2
File Format	PDF
ISBN	0791847985
DOI	10.1115/SBC2007-176190
Conference Proceedings	ASME 2007 Summer Bioengineering Conference
Language	English
Publisher Date	2007-06-20
Publisher Place	Keystone, Colorado, USA
Access Restriction	Subscribed
Subject Keyword	Biomechanics Finite element model Mechanical behavior Lumbar spine Scoliosis Kinematics Disks Biochemistry Intervertebral discs Diseases Testing
Content Type	Text
Resource Type	Article

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