NDLI: The Characterization of Age-Related Human Cortical Bone Porosity, Water Distribution Changes by Nuclear Magnetic Resonance

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Ni, Qingwen Juffry, S. Nyman Wang, Xiaodu Daniel, P. Nicolella
Copyright Year	2007
Abstract	Previous studies have shown that bone fracture toughness is also significantly correlated to changes in porosity, microarchitecture, osteonal morphology, collagen integrity, microdamage, and the interactions of water with collagen and mineral phases, all of which are measures of bone quality. Currently, the influence of water removal on the strength and toughness of cortical bone has studied by Nyman et al [1]. The results have shown that loss of water in the collagen phase decreases the toughness of bone, whereas loss of water associated with the mineral phase decreases both bone strength and toughness. However, in that paper the loss of water was used the dehydration method for such mechanism studies. Here, we hypothesize that the NMR relaxation technique can non-destructively and non-invasively assess the porosity, bound water (water bound to collage and mineral phases) and mobile water (water within the pores).
Sponsorship	Bioengineering Division
Starting Page	7
Ending Page	8
Page Count	2
File Format	PDF
ISBN	0791847985
DOI	10.1115/SBC2007-176213
Conference Proceedings	ASME 2007 Summer Bioengineering Conference
Language	English
Publisher Date	2007-06-20
Publisher Place	Keystone, Colorado, USA
Access Restriction	Subscribed
Subject Keyword	Water Relaxation (physics) Water distribution Bone Nuclear magnetic resonance Porosity Minerals Bone fractures Fracture toughness
Content Type	Text
Resource Type	Article

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