NDLI: Computational Study on the Bridging Vein Rupture of Blast-Induced Traumatic Brain Injury Using a Numerical Human Head Model

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Wang, Chenzhi Pahk, Jae Bum Carey, D. Balaban Jeffrey, S. Vipperman
Copyright Year	2011
Abstract	The occurrence of blast-induced traumatic brain injury (bTBI) in people serving in battle environments is dramatically high. The blast front, or leading edge of the shock wave is a brief, acute overpressure wave that travels supersonically with a magnitude that is several times higher than that of ambient. The shock wave propagates through the human head and injures intracranial tissues. Classical neuropathologic signs of bTBI include cerebral contusion, diffuse axonal injury, subdural hematoma (SDH) and subarachnoid hematoma, of which subdural hematoma is the most dominating sign of bTBI. Here, computational finite element (FE) modeling is used to investigate the mechanical process of bTBI. The overall goal of the present study is to find the injury threshold of the SDH injury due to bTBI, by investigating the biomechanical response of the bridging veins in the human brain under shock wave loading that originates from detonation. This research mainly develops a basic FE human head model which consists of skull and parts of the brain. The geometric models of skull and brain are developed from segmentations of magnetic resonance imaging (MRI) files of a real human head. The boundary conditions on the neck and head are modeled as a displacement-fixed condition. The numerically simulated blast waves are applied on the human head model as external loading conditions. The internal response in the subarachnoid space is used as loadings on the bridging vein submodel. The maximum principal stress of the bridging vein is used to determine the whether there is failure of the bridging vein, thus estimating the “injury threshold” of SDH in bTBI. Results show that 150g TNT blast of 1 meter away from the head can result in a high possibility of SDH occurrence.
Starting Page	111
Ending Page	120
Page Count	10
File Format	PDF
ISBN	9780791854884
DOI	10.1115/IMECE2011-65733
Volume Number	Volume 2: Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology
Conference Proceedings	ASME 2011 International Mechanical Engineering Congress and Exposition
Language	English
Publisher Date	2011-11-11
Publisher Place	Denver, Colorado, USA
Access Restriction	Subscribed
Subject Keyword	Brain Traumatic brain injury Biological tissues Rupture Wounds Explosions Waves Modeling Displacement Stress Biomechanics Shock waves Image segmentation Magnetic resonance imaging Boundary-value problems Finite element analysis Failure
Content Type	Text
Resource Type	Article

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