NDLI: Estimation of Erythrocyte Deformability Using a Viscoelastic Model With Two Degrees of Freedom

Content Provider	The American Society of Mechanical Engineers (ASME) Digital Collection
Author	Mori, Tatsuya Saito, Takashi
Copyright Year	2011
Abstract	An erythrocyte is represented using a viscoelastic model with two degrees of freedom, where a spring was connected parallel to a dashpot to estimate quantitatively the dynamic deformability. To identify such parameters as the elastic modulus and viscous damping coefficient of the model, erythrocytes were deformed using a periodical shear flow field. Displacement of the center of gravity ΔG and the deformation quantity of major axis ΔL were obtained from time series of images. In this paper, erythrocytes from a normal subjects were treated with glutaraldehyde to create variations in hardness and deformability. Both of the data series are periodic on movement and deformation of erythrocytes. Based on the experimental data, parameters of the viscoelastic model were identified. The estimation method of dynamic deformability of erythrocytes was examined.
Starting Page	659
Ending Page	663
Page Count	5
File Format	PDF
ISBN	9780791854884
DOI	10.1115/IMECE2011-63840
Volume Number	Volume 2: Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology
Conference Proceedings	ASME 2011 International Mechanical Engineering Congress and Exposition
Language	English
Publisher Date	2011-11-11
Publisher Place	Denver, Colorado, USA
Access Restriction	Subscribed
Subject Keyword	Damping Elastic moduli Degrees of freedom Deformation Center of mass Shear flow Erythrocytes Time series Shock absorbers Springs Displacement
Content Type	Text
Resource Type	Article

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