NDLI: Variation of cone photoreceptor packing density with retinal eccentricity and age.

Please wait, while we are loading the content...

Year: 2017 Volume: 58

Year: 2016 Volume: 57

Year: 2015 Volume: 56

Year: 2014 Volume: 56

Year: 2014 Volume: 55

Year: 2013 Volume: 54

Year: 2012 Volume: 53

Year: 2011 Volume: 52

Year: 2011 Volume: 52 Issue: 13

Year: 2011 Volume: 52 Issue: 12

Year: 2011 Volume: 52 Issue: 11

Year: 2011 Volume: 52 Issue: 10

Insulin growth factor promotes human corneal fibroblast network formation in vitro.

Macular pigment and visual performance in glare: benefits for photostress recovery, disability glare, and visual discomfort.

Intraocular fluid dynamics and retinal shear stress after vitrectomy and gas tamponade.

Copy number variations and primary open-angle glaucoma.

Shadow removal and contrast enhancement in optical coherence tomography images of the human optic nerve head.

Gene expression and miR profiles of human corneal fibroblasts in response to dexamethasone.

The effect of intravitreal injection of bevacizumab on retinal circulation in patients with neovascular macular degeneration.

Mitochondria-targeted peptide MTP-131 alleviates mitochondrial dysfunction and oxidative damage in human trabecular meshwork cells.

Proteomic profiling of inflammatory signaling molecules in the tears of patients on chronic glaucoma medication.

Simultaneous cell death and upregulation of poly(ADP-ribose) polymerase-1 expression in early postnatal mouse retina.

Vitamin D Enhances Corneal Epithelial Barrier Function

Posterior (outward) migration of the lamina cribrosa and early cupping in monkey experimental glaucoma.

Variation of cone photoreceptor packing density with retinal eccentricity and age.

Efficacy of a web-based intervention to improve and sustain knowledge and screening for amblyopia in primary care settings.

Induction of differentiation by pyruvate and DMEM in the human retinal pigment epithelium cell line ARPE-19.

Prevalence and associations of anisometropia with spherical ametropia, cylindrical power, age, and sex in refractive surgery candidates.

Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells.

Proinflammatory cytokine profiling of tears from dry eye patients by means of antibody microarrays.

Further analysis of the lens phenotype in Lim2-deficient mice.

Tracking dendritic shrinkage of retinal ganglion cells after acute elevation of intraocular pressure.

Placenta microbiology and histology and the risk for severe retinopathy of prematurity.

Photoreceptor structure and function in patients with congenital achromatopsia.

Long-term preservation of cone photoreceptors and restoration of cone function by gene therapy in the guanylate cyclase-1 knockout (GC1KO) mouse.

Fetal check ligament connected between the conjunctiva and the medial and lateral recti.

24-hour IOP telemetry in the nonhuman primate: implant system performance and initial characterization of IOP at multiple timescales.

Hypodense regions (holes) in the retinal nerve fiber layer in frequency-domain OCT scans of glaucoma patients and suspects.

The effect of vasopressin on choroidal blood flow, intraocular pressure, and orbital venous pressure in rabbits.

In vivo ocular fluorophotometry: delivery of fluoresceinated dextrans via transscleral diffusion in rabbits.

Comparison of standard automated perimetry, frequency-doubling technology perimetry, and short-wavelength automated perimetry for detection of glaucoma.

The pattern of learned visual improvements in adult amblyopia.

Rod Sensitivity, Cone Sensitivity, and Photoreceptor Layer Thickness in Retinal Degenerative Diseases

Transforming growth factor-ß inhibition decreases diode laser-induced choroidal neovascularization development in rats: P17 and P144 peptides.

A comprehensive evaluation of the precision (repeatability and reproducibility) of the Oculus Pentacam HR.

Elevated serum osteopontin levels and genetic polymorphisms of osteopontin are associated with Vogt-Koyanagi-Harada disease.

174delG mutation in mouse MFRP causes photoreceptor degeneration and RPE atrophy.

The antiangiogenic effects of integrin alpha5beta1 inhibitor (ATN-161) in vitro and in vivo.

Age-related impairment in choroidal blood flow compensation for arterial blood pressure fluctuation in pigeons.

Lamina-specific anatomic magnetic resonance imaging of the human retina.

Genotype-dependent sensitivity of uveal melanoma cell lines to inhibition of B-Raf, MEK, and Akt kinases: rationale for personalized therapy.

The effects of Mozart's music on the performance of glaucoma patients on automated perimetry.

Choroidal blood flow response to isometric exercise in glaucoma patients and patients with ocular hypertension.

The High-Mobility Group Box-1 Nuclear Factor Mediates Retinal Injury after Ischemia Reperfusion

Hydroxyapatite for keratoprosthesis biointegration.

Analysis of the composition of lipid in human meibum from normal infants, children, adolescents, adults, and adults with meibomian gland dysfunction using ¹H-NMR spectroscopy.

Polyhexamethylene biguanide and calcineurin inhibitors as novel antifungal treatments for Aspergillus keratitis.

Inducers of cross-linked actin networks in trabecular meshwork cells.

Tear production and ocular surface changes in experimental dry eye after elimination of desiccating stress.

Edaravone-loaded liposome eyedrops protect against light-induced retinal damage in mice.

Normative database for corneal backscatter analysis by in vivo confocal microscopy.

Effects of brief daily periods of unrestricted vision during early monocular form deprivation on development of visual area 2.

Tumor-associated lymphangiogenesis in the development of conjunctival melanoma.

Efficacy of a computerized optokinetic nystagmus test in prediction of visual acuity of better than 20/200.

Retinal gene expression and visually evoked behavior in diabetic long evans rats.

Differential association of serum lipids with diabetic retinopathy and diabetic macular edema.

The TAg-RB murine retinoblastoma cell of origin has immunohistochemical features of differentiated Muller glia with progenitor properties.

Differential expression of claudins in retinas during normal development and the angiogenesis of oxygen-induced retinopathy.

Simple estimation of clinically relevant lesion volumes using spectral domain-optical coherence tomography in neovascular age-related macular degeneration.

Racial differences in the prevalence of diabetes but not diabetic retinopathy in a multi-ethnic Asian population.

Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1).

Fluvastatin downregulates VEGF-A expression in TNF- -induced retinal vessel tortuosity.

Mpdz null allele in an avian model of retinal degeneration and mutations in human leber congenital amaurosis and retinitis pigmentosa.

Automated analysis of optic nerve images for detection and staging of papilledema.

Age-related eye disease and mobility limitations in older adults.

Atypical retardation patterns in scanning laser polarimetry are associated with low peripapillary choroidal thickness.

Effect of infliximab on gene expression profiling in Behcet's disease.

The influence of alloxan-induced diabetes on Müller cell contraction-promoting activities in vitreous.

Effects of gelatin hydrogel containing chymase inhibitor on scarring in a canine filtration surgery model.

In vivo cross-sectional observation and thickness measurement of bulbar conjunctiva using optical coherence tomography.

The KORA Eye Study: a population-based study on eye diseases in Southern Germany (KORA F4).

Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe).

Literacy is an independent risk factor for vision impairment and poor visual functioning.

Numerical modeling of paintball impact ocular trauma: identification of progressive injury mechanisms.

PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3.

Semiautomated image processing method for identification and quantification of geographic atrophy in age-related macular degeneration.

Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation.

Molecular chaperone function for myocilin.

Endothelin-1-induced proliferation is reduced and Ca²â º signaling is enhanced in endothelin B-deficient optic nerve head astrocytes.

Cross-sectional sample of peripheral refraction in four meridians in myopes and emmetropes.

Target search and identification performance in low vision patients.

Repair of strabismus and binocular fusion in children with cerebral palsy: gross motor function classification scale.

The small GTPase Rap1 is a novel regulator of RPE cell barrier function.

Elevated systemic neutrophil count in diabetic retinopathy and diabetes: a hospital-based cross-sectional study of 30,793 Korean subjects.

Reduction of apoptosis in ischemic retinas of two mouse models using hyperbaric oxygen treatment.

Photochemical properties of UV Filter molecules of the human eye.

Reduced retinal neovascularization, vascular permeability, and apoptosis in ischemic retinopathy in the absence of prolyl hydroxylase-1 due to the prevention of hyperoxia-induced vascular obliteration.

Identification of the muscarinic acetylcholine receptor subtype mediating cholinergic vasodilation in murine retinal arterioles.

Gene expression profiling of the retina after transcorneal electrical stimulation in wild-type Brown Norway rats.

Assessment of cone survival in response to CNTF, GDNF, and VEGF165b in a novel ex vivo model of end-stage retinitis pigmentosa.

Changes in vision- and health-related quality of life in patients with diabetic macular edema treated with pegaptanib sodium or sham.

Early-stage retinal melatonin synthesis impairment in streptozotocin-induced diabetic wistar rats.

Associations of complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2) genotypes with subtypes of polypoidal choroidal vasculopathy.

Muller glia, vision-guided ocular growth, retinal stem cells, and a little serendipity: the Cogan lecture.

Why HLA-B27? My thirty-year quest: the Friedenwald lecture.

Reflections on 'hot' blind spots: lessons from research on aging macula disorder and glaucoma: the Weisenfeld lecture.

Current gene discovery strategies for ocular conditions.

Year: 2011 Volume: 52 Issue: 9

Year: 2011 Volume: 52 Issue: 8

Year: 2011 Volume: 52 Issue: 7

Year: 2011 Volume: 52 Issue: 6

Year: 2011 Volume: 52 Issue: 5

Year: 2011 Volume: 52 Issue: 4

Year: 2011 Volume: 52 Issue: 3

Year: 2011 Volume: 52 Issue: 2

Year: 2011 Volume: 52 Issue: 1

Year: 2010 Volume: 51

Year: 2009 Volume: 50

Year: 2008 Volume: 49

Variation of cone photoreceptor packing density with retinal eccentricity and age.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Song, Hongxin Zhong, Zhangyi Elsner, Ann E. Chui, Toco Yuen Ping Burns, Stephen A.
Description	Country affiliation: United States Author Affiliation: Song H ( School of Optometry, Indiana University, Bloomington, Indiana 47405, USA.)
Abstract	PURPOSE: To study the variation of cone photoreceptor packing density across the retina in healthy subjects of different ages. METHODS: High-resolution adaptive optics scanning laser ophthalmoscope (AOSLO) systems were used to systematically image the retinas of two groups of subjects of different ages. Ten younger subjects (age range, 22-35 years) and 10 older subjects (age range, 50-65 years) were tested. Strips of cone photoreceptors, approximately 12° × 1.8° long were imaged for each of the four primary retinal meridians: superior, inferior, nasal, and temporal. Cone photoreceptors within the strips were counted, and cone photoreceptor packing density was calculated. Statistical analysis (three-way ANOVA) was used to calculate the interaction for cone photoreceptor packing density between age, meridian, and eccentricity. RESULTS: As expected, cone photoreceptor packing density was higher close to the fovea and decreased with increasing retinal eccentricity from 0.18 to 3.5 mm (â ¼0.6-12°). Older subjects had approximately 75% of the cone density at 0.18 mm (â ¼0.6°), and this difference decreased rapidly with eccentricity, with the two groups having similar cone photoreceptor packing densities beyond 0.5 mm retinal eccentricity on average. CONCLUSIONS: Cone packing density in the living human retina decreases as a function of age within the foveal center with the largest difference being found at our most central measurement site. At all ages, the retina showed meridional difference in cone densities, with cone photoreceptor packing density decreasing faster with increasing eccentricity in the vertical dimensions than in the horizontal dimensions.
ISSN	01460404
e-ISSN	15525783
DOI	10.1167/iovs.11-7199
Journal	Investigative Opthalmology & Visual Science
Issue Number	10
Volume Number	52
Language	English
Publisher	Association for Research in Vision and Ophthalmology
Publisher Date	2011-09-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Aging Physiology Retina Anatomy & Histology Retinal Cone Photoreceptor Cells Cytology Cell Count Lasers Ophthalmoscopes Visual Acuity Research Support, N.i.h., Extramural Discipline Ophthalmology
Content Type	Text
Resource Type	Article
Subject	Ophthalmology Sensory Systems Cellular and Molecular Neuroscience

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in