NDLI: Higher-order aberrations of anterior and posterior corneal surfaces in patients with keratectasia after LASIK.

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Higher-order aberrations of anterior and posterior corneal surfaces in patients with keratectasia after LASIK.

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Higher-order aberrations of anterior and posterior corneal surfaces in patients with keratectasia after LASIK.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Maeda, Naoyuki Nakagawa, Tomoya Fujikado, Takashi Saika, Makoto Koh, Shizuka Nishida, Kohji Kosaki, Ryo
Description	Country affiliation: Japan Author Affiliation: Maeda N ( Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.); Nakagawa T ( Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.); Kosaki R ( Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.); Koh S ( Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.); Saika M ( Research Institute, Optics Laboratory, Topcon Corporation, Tokyo, Japan.); Fujikado T ( Department of Applied Visual Science, Osaka University Graduate School of Medicine, Osaka, Japan.); Nishida K ( Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.)
Abstract	PURPOSE: We investigated higher-order aberrations (HOAs) of the anterior and posterior corneal surfaces in patients with keratectasia after LASIK. METHODS: The subjects comprised four groups: 12 eyes with keratectasia after LASIK, 30 eyes following LASIK without keratectasia, 30 keratoconic eyes, and 30 normal eyes. Corneal HOAs due to the anterior and posterior corneal surfaces for 6-mm pupils (root mean square [µm]) were obtained using a Scheimpflug-based corneal tomographer and compared among the four groups. RESULTS: There were significant differences in total HOAs of the anterior and posterior corneal surfaces (mean ± SD) in the keratectasia (2.49 ± 1.37 and 0.83 ± 0.57), keratoconus (4.50 ± 2.57 and 1.18 ± 0.65), LASIK (0.84 ± 0.25 and 0.14 ± 0.04), and normal (0.52 ± 0.15 and 0.17 ± 0.06) groups except for between keratoconus and keratectasia at the posterior surface. Keratectasia and keratoconus showed similar coma-dominant patterns at both surfaces, and there were no significant differences in the Zernike terms between both groups except for the total HOAs and coma aberration at the anterior surface. CONCLUSIONS: Although flap creation and laser ablation were supposed to center on the primary line of sight in LASIK, keratectasia after LASIK showed coma-dominant HOAs at both corneal surfaces. This suggests that the cornea in keratectasia has optical properties similar to those in keratoconus.
ISSN	01460404
e-ISSN	15525783
Journal	Investigative Opthalmology & Visual Science
Issue Number	6
Volume Number	55
Language	English
Publisher	Association for Research in Vision and Ophthalmology
Publisher Date	2014-05-29
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Corneal Wavefront Aberration Diagnosis Endothelium, Corneal Pathology Epithelium, Corneal Keratoconus Keratomileusis, Laser In Situ Lasers, Excimer Therapeutic Use Postoperative Complications Aberrometry Dilatation, Pathologic Etiology Imaging, Three-dimensional Myopia Surgery Retrospective Studies Observational Study Research Support, Non-u.s. Gov't Discipline Ophthalmology
Content Type	Text
Resource Type	Article
Subject	Ophthalmology Sensory Systems Cellular and Molecular Neuroscience

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