NDLI: From laboratory to environmental conditions: a new approach for chemical's biodegradability assessment.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Armand, Maul François, Brillet Thouand, Gérald Marie-José, Durand
Description	Country affiliation: France Author Affiliation: François B ( Université de Nantes, UMR CNRS 6144 GEPEA, IUT Génie Biologique, La Roche sur Yon, France.); Armand M ( Université de Lorraine, LIEC-UMR CNRS, 7360, Metz, France.); Marie-José D ( Université de Nantes, UMR CNRS 6144 GEPEA, IUT Génie Biologique, La Roche sur Yon, France.); Thouand G ( Université de Nantes, UMR CNRS 6144 GEPEA, IUT Génie Biologique, La Roche sur Yon, France. gerald.thouand@univ-nantes.fr.)
Abstract	With thousands of organic chemicals released every day into our environment, Europe and other continents are confronted with increased risk of health and environmental problems. Even if a strict regulation such as REgistration, Authorization and restriction of CHemicals (REACH) is imposed and followed by industry to ensure that they prove the harmlessness of their substances, not all testing procedures are designed to cope with the complexity of the environment. This is especially true for the evaluation of persistence through biodegradability assessment guidelines. Our new approach has been to adapt 'in the lab' biodegradability assessment to the environmental conditions and model the probability for a biodegradation test to be positive in the form of a logistic function of both the temperature and the viable cell density. Here, a proof of this new concept is proposed with the establishment of tri-dimensional biodegradability profiles of six chemicals (sodium benzoate, 4-nitrophenol, diethylene glycol, 2,4,5-trichlorophenol, atrazine, and glyphosate) between 4 to 30 °C and 10(4) to 10(8) cells ml(-1) as can be found in environmental compartments in time and space. The results show a significant increase of the predictive power of existing screening lab-scale tests designed for soluble substances. This strategy can be complementary to those current testing strategies with the creation of new indicators to quantify environmental persistence using lab-scale tests.
ISSN	09441344
Issue Number	18
Journal	Environmental Science and Pollution Research
Volume Number	23
e-ISSN	16147499
Language	English
Publisher	Springer
Publisher Date	2016-09-01
Publisher Place	Germany
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Environmental Science Discipline Environmental Chemistry
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis Pollution Medicine

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