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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Alfonso, Alejandro Jalal, Ahmed Hasnain Umasankar, Yogeswaran Gonzalez, Pablo J. Bhansali, Shekhar |
| Description | Country affiliation: United States Author Affiliation: Jalal AH ( Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, United States.); Umasankar Y ( Biomolecular Sciences Institute, Florida International University, Miami, FL 33174, United States.); Gonzalez PJ ( Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, United States.); Alfonso A ( Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, United States.); Bhansali S ( Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, United States. Electronic address: sbhansa@fiu.edu.) |
| Abstract | Multimodal electrochemical technique incorporating both open circuit potential (OCP) and amperometric techniques have been conceptualized and implemented to improve the detection of specific analyte in systems where more than one analyte is present. This approach has been demonstrated through the detection of ethanol while eliminating the contribution of water in a micro fuel cell sensor system. The sensor was interfaced with LMP91000 potentiostat, controlled through MSP430F5529LP microcontroller to implement an auto-calibration algorithm tailored to improve the detection of alcohol. The sensor was designed and fabricated as a three electrode system with Nafion as a proton exchange membrane (PEM). The electrochemical signal of the interfering phase (water) was eliminated by implementing the multimodal electrochemical detection technique. The results were validated by comparing sensor and potentiostat performances with a commercial sensor and potentiostat respectively. The results suggest that such a sensing system can detect ethanol at concentrations as low as 5ppm. The structure and properties such as low detection limit, selectivity and miniaturized size enables potential application of this device in wearable transdermal alcohol measurements. |
| ISSN | 09565663 |
| Volume Number | 87 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2017-01-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Biosensing Techniques Instrumentation Electrochemical Techniques Ethanol Analysis Electrodes Equipment Design Fluorocarbon Polymers Chemistry Humans Humidity Limit Of Detection Membranes, Artificial Reproducibility Of Results Skin Water Evaluation Studies Journal Article Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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