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Two case-reports of the limb salvage treatment of osteosarcoma consolidated with obvious pathological fractures.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Cui, Q. Li, D. F. Liu, C. Guo, J. Liu, S. B. Liu, Y. S. Zhai, J. M. Zeng, Yanjun
Description	Country affiliation: China Author Affiliation: Cui Q ( Department of Bone Tumor, Academy of Military Medical Sciences, No.8 of East Avenue, Fengtai District, Beijing 100071, China.)
Abstract	OBJECTIVE: The effect of the limb salvage of the treatment of Osteosarcoma Consolidated with Obvious Pathological Fractures is not very well, the purpose of this paper is to track the efficacy of limb salvage treatment when the patients accepted the artery intervention chemotherapy and enclosed 2 clinical case-reports. METHODS: From January 2003 to September 2005, 2 clinical cases which one is a male, 29 years old, was confirmed osteosarcoma on the left distal femur, and the other is a female, 15 years old and has osteosarcoma on the right arm with obvious pathological fracture. After receiving arterial chemotherapy pump embedded, then started chemotherapy after the tumor biopsy, and the next process prosthesis replacement in limb salvage surgery after 5 times chemotherapy, follow on the next 5 times chemotherapy after the surgery. RESULTS: With an average follow-up 70 months, there are no postoperative infection and prosthesis loosening found, also didn't detected tumor recurrence and metastasis, and the limb function recovered well. CONCLUSIONS: With the effective, neoadjuvant chemotherapy and comprehensive treatment, salvage treatment is not the contraindication of the patients with pathological fractures of combined primary osteosarcoma, and the treatment with long-term follow-up effectively.
File Format	HTM / HTML
ISSN	12194956
Issue Number	4
Volume Number	17
e-ISSN	15322807
Journal	Pathology & Oncology Research
Language	English
Publisher	Springer
Publisher Date	2011-12-01
Publisher Place	Netherlands
Access Restriction	Subscribed
Subject Keyword	Discipline Oncology Bone Neoplasms Drug Therapy Surgery Fractures, Spontaneous Limb Salvage Methods Osteosarcoma Adolescent Adult Pathology Female Follow-up Studies Humans Male Neoadjuvant Therapy Case Reports Journal Article
Content Type	Text
Resource Type	Case study Article
Subject	Cancer Research Pathology and Forensic Medicine Oncology

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