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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Tacher, Vania Lin, Mingde Bhagat, Nikhil Abi Jaoudeh, Nadine Radaelli, Alessandro Noordhoek, Niels Carelsen, Bart Wood, Bradford J. Geschwind, Jean-François |
| Description | Author Affiliation: Tacher V ( Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital.) |
| Abstract | The advent of cone-beam computed tomography (CBCT) in the angiography suite has been revolutionary in interventional radiology. CBCT offers 3 dimensional (3D) diagnostic imaging in the interventional suite and can enhance minimally-invasive therapy beyond the limitations of 2D angiography alone. The role of CBCT has been recognized in transarterial chemo-embolization (TACE) treatment of hepatocellular carcinoma (HCC). The recent introduction of a CBCT technique: dual-phase CBCT (DP-CBCT) improves intra-arterial HCC treatment with drug-eluting beads (DEB-TACE). DP-CBCT can be used to localize liver tumors with the diagnostic accuracy of multi-phasic multidetector computed tomography (M-MDCT) and contrast enhanced magnetic resonance imaging (CE-MRI) (See the tumor), to guide intra-arterially guidewire and microcatheter to the desired location for selective therapy (Reach the tumor), and to evaluate treatment success during the procedure (Treat the tumor). The purpose of this manuscript is to illustrate how DP-CBCT is used in DEB-TACE to see, reach, and treat HCC. |
| File Format | HTM / HTML |
| e-ISSN | 1940087X |
| DOI | 10.3791/50795 |
| Journal | Journal of Visualized Experiments |
| Issue Number | 82 |
| Language | English |
| Publisher | MyJove Corp. |
| Publisher Date | 2013-12-02 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Discipline Physical Sciences Discipline Life Sciences Discipline Medicine Carcinoma, Hepatocellular Therapy Chemoembolization, Therapeutic Liver Neoplasms Angiography Instrumentation Blood Supply Cone-beam Computed Tomography Doxorubicin Administration & Dosage Fluoroscopy Hepatic Artery Physiology Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't Video-audio Media |
| Content Type | Text |
| Resource Type | Case study Article |
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