NDLI: Apple and pear consumption and type 2 diabetes mellitus risk: a meta-analysis of prospective cohort studies

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Food & Function Vol - 8 Issue - 2

Food & Function Vol - 8 Issue - 1

Food & Function Vol -7

Food & Function Vol -6

Food & Function Vol -5

Food & Function Vol -4

Food & Function Vol -3

Food & Function Vol -2

Food & Function Vol -1

Apple and pear consumption and type 2 diabetes mellitus risk: a meta-analysis of prospective cohort studies

Content Provider	Royal Society of Chemistry (RSC)
Author	Yang, Bo Jiang, Jia-Jing Tang, Jun Guo, Xiao-fei Li, Duo
Copyright Year	2017
Abstract	The conclusions from epidemiological studies are controversial between apple and pear consumption and type 2 diabetes mellitus (T2DM) risk. The present study aimed to investigate whether apple and pear consumption was inversely associated with T2DM risk, and to evaluate the potential dose–response relationship. The Cochrane library, Embase and PubMed databases were searched up to Nov 2016. Prospective cohort studies, which reported the association of apple and pear consumption with incidence of T2DM, were included. Multivariate-adjusted relative risks (RRs) for the highest versus lowest category were combined by using a random-effects model. A restricted cubic spline regression model was performed to examine the dose–response relationship. A total of 5 independent prospective cohort studies were included (14 120 T2DM incident cases and 228 315 participants). The summary estimate showed that consumption of apples and pears was associated with 18% reduction in T2DM risk (95% confidence interval (CI): 0.75, 0.88; I2 = 0.00%). Dose–response analysis showed that one serving per week increment of apple and pear consumption was associated with a 3% (95% CI: 0.96, 0.98; p for trend <0.001) reduction in T2DM risk. The present meta-analysis provides significant evidence of an inverse association between apple and pear consumption and T2DM risk.
Starting Page	927
Ending Page	934
Page Count	8
File Format	HTM / HTML PDF
ISSN	20426496
Volume Number	8
Issue Number	3
Journal	Food & Function
DOI	10.1039/c6fo01378c
Language	English
Publisher	Royal Society of Chemistry
Access Restriction	Open
Subject Keyword	Embase Pear Diabetes mellitus type 2 Dose\u2013response relationship Cochrane Library PubMed Cohort study Cubic Hermite spline Regression analysis Prospective cohort study Confidence interval Meta-analysis
Content Type	Text
Resource Type	Article
Subject	Medicine Food Science

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