NDLI: Construction of Artificial Cell Membranes having Lipid Microdomains for Molecular Information Processing

Content Provider	IEEE Xplore Digital Library
Author	Yasuhara, K. Zhonghua Wang Hirata, K. Sasaki, Y. Kikuchi, J.-i.
Copyright Year	2008
Description	Author affiliation: Grad. Sch. of Mater. Sci., Nara Inst. of Sci. & Technol., Ikoma (Yasuhara, K.; Zhonghua Wang; Hirata, K.; Sasaki, Y.; Kikuchi, J.-i.)
Abstract	Lipid microdomain formation in artificial cell membranes was investigated in relation to biologically important lipid rafts present in the cytoplasmic membranes. In order to imaging lipid microdomains, we developed a novel molecular sensor composed of a fluorescent auramine head, a hydrophobic cholesterol moiety, and a szlig-alanine unit connecting them. Fluorescence intensity of the molecular sensor was sensitive to microenvironmental viscosity. Thus, the molecule acted as an effective fluorescent sensor being capable of imaging lipid microdomains with different viscosities on giant liposomes. We also prepared an azobenzene-modified cholesterol derivative for photo-induced morphological changes in lipid bilayer membranes. Upon ultraviolet light irradiation, the cholesterol derivative embedded in a liposomal membrane with domain structures changed its conformation through photoisomerization of the azobenzene moiety to induce transformation of the lipid microdomain. Lipid microdomain formation was achieved not only in liposomes but also in the mixed lipid membranes formed with cerasome, which provided an effective platform for construction of artificial signal transduction systems.
Starting Page	77
Ending Page	82
File Size	5394276
Page Count	6
File Format	PDF
ISBN	9781424429189
DOI	10.1109/MHS.2008.4752426
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-11-06
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Cells (biology) Biomembranes Lipidomics Information processing Fluorescence Image sensors Biosensors Viscosity Head Joining processes
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Construction and Characterization of Soft-Supported Lipid Bilayer Membranes for Biosensors Application

Molecular Rheology In Biological Membranes

MEMS technology for Artificial Cells

Detecting membrane lipid microdomains by two-photon fluorescence microscopy

Quantitative imaging of molecular order in lipid membranes using two-photon fluorescence polarimetry

Rapid, multipoint molecular spectroscopic measurements of shear effects on endothelial cell membranes

Photoreceptor ion channels reconstituted in bilayer lipid membranes

Pico-liter injection control to individual nano-liter solution coated by lipid layer

Characterisation of chlorpromazine binding to lipid bilayer membranes

Construction of Artificial Cell Membranes having Lipid Microdomains for Molecular Information Processing

Similar Documents

Construction and Characterization of Soft-Supported Lipid Bilayer Membranes for Biosensors Application

Molecular Rheology In Biological Membranes

MEMS technology for Artificial Cells

Detecting membrane lipid microdomains by two-photon fluorescence microscopy

Quantitative imaging of molecular order in lipid membranes using two-photon fluorescence polarimetry

Rapid, multipoint molecular spectroscopic measurements of shear effects on endothelial cell membranes

Photoreceptor ion channels reconstituted in bilayer lipid membranes

Pico-liter injection control to individual nano-liter solution coated by lipid layer

Characterisation of chlorpromazine binding to lipid bilayer membranes

Construction of Artificial Cell Membranes having Lipid Microdomains for Molecular Information Processing