NDLI: Coil design considerations for deep-brain transcranial magnetic stimulation (dTMS)

Content Provider	IEEE Xplore Digital Library
Author	Deng, Zhi-De Peterchev, Angel V. Lisanby, Sarah H.
Copyright Year	2008
Description	Author affiliation: Department of Electrical Engineering and with the Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University, New York, 10032, USA (Deng, Zhi-De) \|\| Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University / New York State Psychiatric Institute, New York, 10032, USA (Peterchev, Angel V.; Lisanby, Sarah H.)
Abstract	Deep-brain transcranial magnetic stimulation (dTMS) could provide new, non-invasive therapeutic options for various psychiatric and neurological disorders. Figures of merit (FoMs) are proposed to evaluate and compare dTMS coil designs. These FoMs characterize the depth of electric field penetration, scalp stimulation, focality, and energy. Two coil configurations potentially suitable for dTMS are analyzed: circular crown coil and C-core coil. These coils have significantly less attenuation of the electric field strength in depth, compared to conventional TMS coils. In the limiting case as the coil dimensions become large relative to the head, the electric field decay in depth becomes linear, which indicates that, at best, the electric field attenuation is directly proportional to the depth of the target. The charge density and heating induced in the brain are at safe levels, but the risk of unintended neuromodulation and seizures with dTMS has to be evaluated further. Preliminary simulation results suggest that the crown coil has the best overall performance for dTMS. Finally, synchronous firing of all TMS coil elements appears more effective at stimulating deep neurons than is sequential firing.
Starting Page	5675
Ending Page	5679
File Size	410150
Page Count	5
File Format	PDF
ISBN	9781424418145
ISSN	1557170X
DOI	10.1109/IEMBS.2008.4650502
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-08-20
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	safety Deep brain stimulation transcranial magnetic stimulation TMS coils electromagnetic induction electric fields focusing energy
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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