NDLI: Comparison of electrically-evoked ganglion cell responses in normal and degenerate retina

Content Provider	IEEE Xplore Digital Library
Author	Ye, Jang Hee Kim, Kyung Hwan Goo, Yong Sook
Copyright Year	2008
Description	Author affiliation: Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Republic of Korea (Kim, Kyung Hwan) \|\| Department of Physiology, Chungbuk National University Medical School, Cheongju, Republic of Korea (Ye, Jang Hee; Goo, Yong Sook)
Abstract	Retinal prosthesis is regarded as a promising method for restoring vision for the blind with retinal diseases such as retinitis pigmentosa (RP) and age related macular degeneration (ARMD). Among the several prerequisites for retinal prosthesis to succeed, one of the most important factors is the optimization of electrical stimulation applied through the prosthesis. From the previous study, we showed that the electrical characteristics of diseased retina are different from those of normal retina. For the next step, we compared electrically evoked response properties of retinal ganglion cells and established the thresholds for charge density in normal and rd1 mouse using multi-electrode array (MEA). The threshold for charge density was higher in rd1 mouse. The mean values were 254.78 $μC/cm^{2}$ and 424.62 $μC/cm^{2}$ in normal and rd1 mouse, respectively.
Starting Page	2465
Ending Page	2468
File Size	259940
Page Count	4
File Format	PDF
ISBN	9781424418145
ISSN	1557170X
DOI	10.1109/IEMBS.2008.4649699
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-08-20
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	rd1 mouse retinal prosthesis retinal ganglion cell multi-electrode array (MEA)
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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Retinal ganglion cell (RGC) responses to different voltage stimulation parameters in rd1 mouse retina

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