NDLI: Photoacoustic depth profiling of a skin model for non-invasive glucose measurement

Content Provider	IEEE Xplore Digital Library
Author	Wadamori, Naoki Shinohara, Ryou Ishihara, Yasutoshi
Copyright Year	2008
Description	Author affiliation: Department of Electrical Engineering, Nagaoka University of Technology, Niigata 940-2188 Japan (Wadamori, Naoki; Shinohara, Ryou; Ishihara, Yasutoshi)
Abstract	A measurable depth of the blood glucose level by using photoacoustic spectroscopy (PAS) was discussed experimentally in order to improve detection sensitivity. Since a measurable depth of the PAS depends on a modulation frequency of the chopped light irradiated to a sample, the relationship between modulation frequency and the thickness of a sample was evaluated. The photoacoustic detector used in these experiments consisted of an acoustic resonance pipe and an optical microphone, and a two-layer model composed of silicone sheets with the different optical absorption. The measurable depth was 2–3 mm with modulation frequency of 1000–2000 Hz. Furthermore, the reason for the measurable depth to be deeper than the thermal diffusion length of the sample was discussed theoretically. From these analyses of thermoelastic wave, the relation between the photoacoustic signal propagation and the measurable depth in a tissue was clarified.
Starting Page	5644
Ending Page	5647
File Size	509597
Page Count	4
File Format	PDF
ISBN	9781424418145
ISSN	1557170X
DOI	10.1109/IEMBS.2008.4650494
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-08-20
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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