NDLI: Robust control for propofol induced anesthesia based on Second-Order Sliding-Mode Control

Content Provider	IEEE Xplore Digital Library
Author	Gallardo Hernandez, A.G. Fridman, L. Eslava Escobar, A. Davila, J. Leder, R. Revilla Monsalve, C. Islas Andrade, S. Hernandez, A.L.
Copyright Year	2013
Description	Author affiliation: Dept. of Control, Univ. Nac. Autonoma de Mexico (UNAM), Mexico City, Mexico (Fridman, L.; Eslava Escobar, A.; Leder, R.) \|\| Sect. of Grad. Studies & Res., Nat. Polytech. Inst. (IPN), Mexico City, Mexico (Davila, J.) \|\| Centro Medico Nac. Siglo XXI, Mexico City, Mexico (Gallardo Hernandez, A.G.; Revilla Monsalve, C.; Islas Andrade, S.; Hernandez, A.L.)
Abstract	The effect of anesthesia can be different in every patient. It is often the case that anesthesia has to be induced in emergency situations, where identification of the patient's parameters cannot be done. It is preferable to have a controller insensitive to parameter variations, such as Second-Order Sliding-ModeControl (SOSMC). This kind of controller is also robust with respect to singular perturbations that may occur during surgery; therefore SOSMC is well suited to perform a closed loop propofol dosage. This in silico study tests the performance of an SOSMC for 4 different patients, to evaluate its insensibility to parameter variation (interpatient variability). SOSMC robustness with respect to perturbations is evaluated by a bleeding simulation, that changes the parameters of the pharmacokinetic model (intrapatient variability), and also by inducing a surgical stimuli.
Sponsorship	IEEE Control Syst. Soc.
Starting Page	2864
Ending Page	2869
File Size	379093
Page Count	6
File Format	PDF
ISBN	9781467357142
ISSN	07431546
e-ISBN	9781467357173
DOI	10.1109/CDC.2013.6760318
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-12-10
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Surgery Anesthesia Drugs Hemorrhaging Brain modeling Monitoring Robustness
Content Type	Text
Resource Type	Article
Subject	Control and Optimization Control and Systems Engineering Modeling and Simulation

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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