NDLI: Imaging of Magnetic Nanoparticles Using Second-Harmonic Signals

Content Provider	IEEE Xplore Digital Library
Author	Tanaka, S. Oishi, T. Suzuki, T. Ohtani, T. Ariyoshi, S.
Copyright Year	1965
Abstract	Magnetic nanoparticle imaging (MPI) utilizes the non-linear magnetization response M for the detection of superparamagnetic iron oxide magnetic nanoparticles (MNPs). When an external ac magnetic field is applied to the MNPs, some harmonic responses such as second, third, and higher ones arise. We propose and demonstrate that the use of the second-harmonic response is the most effective technique to enhance the signal. The advantage of using the second-harmonic response is that the response can be measured even in a small ac field. A 2-D MPI system using this technique was realized and its performance was evaluated. The MPI system has no mechanical parts but instead magnetically scans an MNP phantom by changing the dc bias field in two directions. The cosine component of the signal is detected by a lock-in-amplifier and differentiated in one direction. The image of the phantom is then reconstructed using the d(cosθ)/dz data. As a result, the position of the phantom may be identified down to the iron content of 9 μg.
Sponsorship	IEEE Magnetics Society
Starting Page	1
Ending Page	4
Page Count	4
File Size	1374616
File Format	PDF
ISSN	00189464
Volume Number	51
Issue Number	11
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-01-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Harmonic analysis Coils Magnetic resonance imaging Phantoms Iron Magnetic separation SQUID magnetic nano-particles second harmonic superconducting Interference Device (SQUID) Magnetic nanoparticle imaging (MPI) magnetic nanoparticles (MNPs)
Content Type	Text
Resource Type	Article
Subject	Electronic, Optical and Magnetic Materials Electrical and Electronic Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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