NDLI: Dendritic cells and B cells: unexpected partners in Th2 development.

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Dendritic cells and B cells: unexpected partners in Th2 development.

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Dendritic cells and B cells: unexpected partners in Th2 development.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Lund, Frances E. León, Beatriz Ballesteros-Tato, André
Description	Author Affiliation: León B ( Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294); Ballesteros-Tato A ( Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294.); Lund FE ( Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294)
Abstract	Although we have known for decades that B cells contribute to immune responses by secreting Ab, it is now clear that they are more than simply factories for Ig production, and they also play key roles as modulators of T cell-dependent immunity. Indeed, the evidence showing that Ag-presenting and cytokine-producing B cells can alter the magnitude and quality of CD4 T cell responses continues to grow. In this article, we review the data showing that B cells, working in partnership with dendritic cells, regulate the development of Th2 cells and the subsequent allergic response.
ISSN	00221767
e-ISSN	15506606
DOI	10.4049/jimmunol.1400149
Journal	The Journal of Immunology
Issue Number	4
Volume Number	193
Language	English
Publisher	The American Association of Immunologists
Publisher Date	2014-08-15
Publisher Place	United States
Access Restriction	Open
Subject Keyword	B-lymphocytes Immunology Dendritic Cells Hypersensitivity Th2 Cells Animals Cell Differentiation Histocompatibility Antigens Class Ii Genetics Lymphocyte Activation Mice Research Support, N.i.h., Extramural Discipline Immunology
Content Type	Text
Resource Type	Article
Subject	Immunology and Allergy Immunology

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