NDLI: Generally detected genes in comparative transcriptomics in bivalves: toward the identification of molecular markers of cellular stress response.

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Generally detected genes in comparative transcriptomics in bivalves: toward the identification of molecular markers of cellular stress response.

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Generally detected genes in comparative transcriptomics in bivalves: toward the identification of molecular markers of cellular stress response.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Miao, Jingjing Chi, Luping Pan, Luqing Song, Ying
Description	Author Affiliation: Miao J ( The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, PR China.); Chi L ( The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, PR China.); Pan L ( The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, PR China. Electronic address: panlq@ouc.edu.cn.); Song Y ( The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, PR China.)
Abstract	The specificity and representativeness of protein-coding genes identified by transcriptomics as biomarkers for environmental toxicological stress is crucial. We extracted the differential gene expression profile data from 49 published comparative transcriptomic studies of bivalves from January 2004 till November 2014 performed in 15 different bivalve species. Among the studies, 77 protein-coding genes were frequently detected when we use threefold of the average detection frequency as cut-off. Cellular organization and communication, protein and energy metabolism, stress response are the main functional classes of these proteins. We consider if these protein-coding genes represent common cellular stress responses of bivalves.
File Format	HTM / HTML
ISSN	13826689
Issue Number	1
Volume Number	39
e-ISSN	18727077
Journal	Environmental Toxicology and Pharmacology
Language	English
Publisher	Elsevier
Publisher Date	2015-01-01
Publisher Place	Netherlands
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Environmental Health Discipline Pharmacology Bivalvia Genetics Stress, Physiological Animals Biological Markers Drug Effects Environmental Pollutants Toxicity Gene Ontology Metals, Heavy Transcriptome Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Medicine Toxicology Pharmacology

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