NDLI: Toxicological evaluation of two pedigrees of clam Ruditapes philippinarum as bioindicators of heavy metal contaminants using metabolomics.

Please wait, while we are loading the content...

Year: 2017 Volume: 51

Year: 2017 Volume: 50

Year: 2017 Volume: 49

Year: 2016 Volume: 49

Year: 2016 Volume: 48

Year: 2016 Volume: 47

Year: 2016 Volume: 46

Year: 2016 Volume: 45

Year: 2016 Volume: 44

Year: 2016 Volume: 43

Year: 2016 Volume: 42

Year: 2016 Volume: 41

Year: 2015 Volume: 40

Year: 2015 Volume: 39

Year: 2015 Volume: 39 Issue: 3

Year: 2015 Volume: 39 Issue: 2

Fenton-like reaction: a possible way to efficiently remove illicit drugs and pharmaceuticals from wastewater.

Correlation of melanophore index with a battery of functional genomic stress indicators for measurement of environmental stress in aquatic ecosystem.

Zn(II)-curcumin protects against oxidative stress, deleterious changes in sperm parameters and histological alterations in a male mouse model of cyclophosphamide-induced reproductive damage.

Toxicity of the insecticide chlorpyrifos to the South American toad Rhinella arenarum at larval developmental stage.

Metabolic pathways of decabromodiphenyl ether (BDE209) in rainbow trout (Oncorhynchus mykiss) via intraperitoneal injection.

Toxicological evaluation of two pedigrees of clam Ruditapes philippinarum as bioindicators of heavy metal contaminants using metabolomics.

Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites.

The effect of mono-(2-ethylhexyl) phthalate on apoptosis of rat ovarian granulosa cells in vitro.

Poly(vinyl alcohol)-coated silver nanoparticles: activation of neutrophils and nanotoxicology effects in human hepatocarcinoma and mononuclear cells.

Analysis of genotoxic activity of ketamine and rocuronium bromide using the somatic mutation and recombination test in Drosophila melanogaster.

Comparison of the in vitro effects of TCDD, PCB 126 and PCB 153 on thyroid-restricted gene expression and thyroid hormone secretion by the chicken thyroid gland.

Immunomodulatory role of piperine in deltamethrin induced thymic apoptosis and altered immune functions.

Growth and migration of LNCaP prostate cancer cells are promoted by triclosan and benzophenone-1 via an androgen receptor signaling pathway.

Tnf- inhibition by infliximab as a new target for the prevention of glycerol-contrast-induced nephropathy.

Environmental factors and apoptotic indices in patients with intrauterine growth retardation: a nested case-control study.

Hexestrol- and nonylphenol-induced differential vitellogenin synthesis in female and male barfin plaice Liopsetta pinnifasciata.

Low water conductivity increases the effects of copper on the serum parameters in fish (Oreochromis niloticus).

Aniline exposure associated with up-regulated transcriptional responses of three glutathione S-transferase Delta genes in Drosophila melanogaster.

Highly selective biomarkers for pesticides developed in Eisenia fetida using SELDI-TOF MS.

Association of arsenic exposure with smoking, alcohol, and caffeine consumption: data from NHANES 2005-2010.

Malathion-induced testicular toxicity is associated with spermatogenic apoptosis and alterations in testicular enzymes and hormone levels in male Wistar rats.

Synergistic effect of non-ionic surfactants Tween 80 and PEG6000 on cytotoxicity of insecticides.

Protective effects of caffeic acid phenethyl ester against acute radiation-induced hepatic injury in rats.

BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathway.

The toxicological effects of thiamethoxam on Gammarus kischineffensis (Schellenberg 1937) (Crustacea: Amphipoda).

Epothilone B induces human ovarian cancer OV-90 cell apoptosis via external pathway.

Synthesis and dose interval dependent hepatotoxicity evaluation of intravenously administered polyethylene glycol-8000 coated ultra-small superparamagnetic iron oxide nanoparticle on Wistar rats.

Characterization of green synthesized nano-formulation (ZnO-A. vera) and their antibacterial activity against pathogens.

Colour changes in Labeo rohita (Ham.) due to pigment translocation in melanophores, on exposure to municipal wastewater of Tung Dhab drain, Amritsar, India.

Effects of lead and cadmium co-exposure on hemoglobin in a Chinese population.

Gallic acid isolated from Spirogyra sp. improves cardiovascular disease through a vasorelaxant and antihypertensive effect.

Levels of caffeine and its metabolites among U.S. smokers and nonsmokers.

Deferasirox-induced cytogenetic responses.

Foodborne mycotoxicoses, risk assessment and underestimated hazard of masked mycotoxins and joint mycotoxin effects or interaction.

Enantioselective apoptosis induced by individual isomers of bifenthrin in Hep G2 cells.

Mitogen-activated protein kinase and Akt pathways are involved in 4-n-nonyphenol induced apoptosis in mouse Sertoli TM4 cells.

Effect of low carbohydrate high protein (LCHP) diet on lipid metabolism, liver and kidney function in rats.

The toxicological impacts of some heavy metals on carbonic anhydrase from gilthead sea bream (Sparus aurata) gills.

PM10 in a background urban site: chemical characteristics and biological effects.

Organic extracts from African dust storms stimulate oxidative stress and induce inflammatory responses in human lung cells through Nrf2 but not NF-κB.

Concentration-dependent effect of photoluminescent carbon dots on the microbial activity of the soil studied by combination methods.

Chronic exposure to cigarette smoke causes extrapulmonary abnormalities in rats.

In vitro cytotoxicity of gold nanorods in A549 cells.

Titanium dioxide nanoparticles exacerbate pneumonia in respiratory syncytial virus (RSV)-infected mice.

Toxicity effects of profenofos on embryonic and larval development of Zebrafish (Danio rerio).

Inhibitory effects of pain relief drugs on neurological enzymes: implications on their potential neurotoxicity to aquatic animals.

The development of the LC-MS/MS method based on S-9 biotransformation for detection of metabolites of selected ß-adrenolytics in surface water.

The inflammasome accelerates radiation-induced lung inflammation and fibrosis in mice.

Altered profile of gut microbiota after subchronic exposure to neochamaejasmin A in rats.

Effects of N-Butylphthalide on the expressions of Nogo/NgR in rat brain tissue after carbon monoxide poisoning.

2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice.

Assessing estrogenic activity and reproductive toxicity of organic extracts in WWTP effluents.

Exposure to bisphenol-A and reproductive hormones among male adults.

Fate of psychoactive compounds in wastewater treatment plant and the possibility of their degradation using aquatic plants.

The arsenic accumulation and its effect on oxidative stress responses in juvenile rockfish, Sebastes schlegelii, exposed to waterborne arsenic (As3+).

Naringin attenuates the cytotoxicity of hepatotoxin microcystin-LR by the curious mechanisms to OATP1B1- and OATP1B3-expressing cells.

Esculetin induces death of human colon cancer cells via the reactive oxygen species-mediated mitochondrial apoptosis pathway.

Anti-hyperplasia effects of Rosa rugosa polyphenols in rats with hyperplasia of mammary gland.

Year: 2015 Volume: 39 Issue: 1

Year: 2014 Volume: 38

Year: 2014 Volume: 37

Year: 2013 Volume: 36

Year: 2013 Volume: 35

Year: 2012 Volume: 34

Year: 2012 Volume: 33

Year: 2011 Volume: 32

Year: 2011 Volume: 31

Year: 2010 Volume: 30

Year: 2010 Volume: 29

Year: 2009 Volume: 28

Year: 2009 Volume: 27

Year: 2008 Volume: 26

Year: 2008 Volume: 25

Year: 2007 Volume: 24

Year: 2007 Volume: 23

Year: 2006 Volume: 22

Year: 2006 Volume: 21

Year: 2005 Volume: 20

Year: 2005 Volume: 19

Year: 2004 Volume: 18

Year: 2004 Volume: 17

Year: 2004 Volume: 16

Year: 2004 Volume: 15

Year: 2003 Volume: 15

Year: 2003 Volume: 14

Year: 2003 Volume: 13

Year: 1996 Volume: 2

Year: 1996 Volume: 1

Toxicological evaluation of two pedigrees of clam Ruditapes philippinarum as bioindicators of heavy metal contaminants using metabolomics.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ji, Chenglong Cao, Lulu Li, Fei
Description	Author Affiliation: Ji C ( Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS)); Cao L ( Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS)); Li F ( Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS))
Abstract	Heavy metal pollution has been of great concern in the Bohai marine environment. Manila clam Ruditapes philippinarum has been used as a bioindicator in marine toxicology. In this study, NMR-based metabolomics was used to ascertain whether there were significant biological differences between two dominant pedigrees (White and Zebra) of clam and evaluate the suitability of two pedigrees for marine environmental toxicology, together with antioxidant enzymatic analysis. Our results indicated that there were significant biological differences between White and Zebra clams based on the metabolic profiles and antioxidant enzyme activities. In details, the metabolic profiles showed higher levels of amino acids and succinate in Zebra clam digestive glands and higher levels of ATP in White clam digestive glands, respectively. The superoxide dismutase activities in control White and Zebra clam samples were significantly different. Additionally, White clam was more sensitive to Cd based on the significant accumulation of Cd, antioxidant enzymatic alterations and sensitive metabolic changes. Overall, we concluded that White clam could be a preferable bioindicator for marine environmental toxicology.
File Format	HTM / HTML
ISSN	13826689
Issue Number	2
Volume Number	39
e-ISSN	18727077
Journal	Environmental Toxicology and Pharmacology
Language	English
Publisher	Elsevier
Publisher Date	2015-03-01
Publisher Place	Netherlands
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Environmental Health Discipline Pharmacology Bivalvia Metabolism Cadmium Toxicity Water Pollutants, Chemical Zinc Animals Environmental Monitoring Gastrointestinal Tract Drug Effects Glutathione Peroxidase Glutathione Transferase Metabolomics Pedigree Superoxide Dismutase Comparative Study Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Medicine Toxicology Pharmacology

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in