NDLI: Use of a poly(ether imide) coating to improve corrosion resistance and biocompatibility of magnesium (Mg) implant for orthopedic applications.

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Use of a poly(ether imide) coating to improve corrosion resistance and biocompatibility of magnesium (Mg) implant for orthopedic applications.

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Use of a poly(ether imide) coating to improve corrosion resistance and biocompatibility of magnesium (Mg) implant for orthopedic applications.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kim, Sang-Bok Jo, Ji-Hoon Lee, Sung-Mi Kim, Hyoun-Ee Shin, Kwan-Ha Koh, Young-Hag
Description	Author Affiliation: Kim SB ( Department of Materials Science and Engineering, WCU Hybrid Materials Program, Seoul National University, Seoul 151-744, Korea.)
Abstract	This study investigated the utility of poly(ether imide) (PEI) coating for improving the corrosion resistance and biocompatibility of magnesium (Mg) implants for orthopedic application. In particular, the microstructure of the PEI coating layers was controlled by the adjustment of the temperature used to dry the spin-coated wet PEI films. When a wet PEI film was dried at 4°C, a relatively thick and porous coating layer was achieved as a result of an extensive exchange of the solvent with water in a moist environment. In contrast, when a wet PEI film was dried at 70°C, a relatively thin and dense layer was created due to the faster evaporation of the solvent with a negligible exchange of the solvent with water. The porous PEI coating layer showed higher stability than did the dense one when immersed in a simulated body fluid (SBF), which was presumably attributed to the formation of chemical bonding between the PEI and the Mg substrate. Both the porous and the dense PEI coated Mg specimens showed significantly improved in vitro biocompatibility, which were assessed in terms of cell attachment, proliferation and differentiation. However, interestingly, the dense PEI coating layer showed greater cell proliferation and differentiation than did the porous layer. .
File Format	HTM / HTML
ISSN	15493296
Issue Number	6
Volume Number	101
e-ISSN	15524965
Journal	Journal of Biomedical Materials Research Part A
Language	English
Publisher	Wiley
Publisher Date	2013-06-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Research Support, Non-u.s. Gov't X-ray Diffraction Cytology Spectrometry, X-ray Emission Alkaline Phosphatase Spectroscopy, Fourier Transform Infrared Osteoblasts Journal Article Ultrastructure Magnesium Hydrogen-ion Concentration Polymers Cell Line Adhesiveness Materials Testing Ions Pharmacology Coated Materials, Biocompatible Metabolism Drug Effects Discipline Biomedical Engineering Chemistry Animals Corrosion Orthopedics Biocompatible Materials Mice Porosity Enzymology Prostheses And Implants Methods
Content Type	Text
Resource Type	Article
Subject	Ceramics and Composites Metals and Alloys Biomaterials Biomedical Engineering

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