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| Content Provider | IET Digital Library |
|---|---|
| Author | Amareh, Nazanin Panahi, Homayon Ahmad Moeinpour, Farid |
| Abstract | Magnetite nanoparticles (MNPs) were synthesised and grafted with polymer containing brilliant cresyl blue for the exchange of losartan potassium. The resulted polymeric nanoparticles were characterised with Fourier transform infrared spectroscopy, elemental analysis, thermogravimetric analysis and transmission electron microscopy. The effects of the exchange parameters such as sample pH, temperature and contact time on sorption of losartan potassium were investigated. The sorption capacity of the functionalised sorbent was 19.4 mg g−1. The equilibrium adsorption data of losartan potassium on modified nanoparticles were analysed by Langmuir, Freundlich, Temkin, Dubinin–Radushkevich and Redlich–Peterson equations. Nearly, 74% of losartan potassium was released in simulated gastric fluid of pH 1.2 in 15 h and 50% in simulated intestinal fluid pH 7.4 in 30 h. These results have shown the utility of losartan potassium loaded–modified MNPs for enteric drug delivery. |
| Starting Page | 1126 |
| Ending Page | 1131 |
| Page Count | 6 |
| Volume Number | 13 |
| e-ISSN | 17500443 |
| Issue Number | Issue 8, Aug (2018) |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/mnl/13/8 |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/10.1049/mnl.2018.0141 |
| Journal | Micro & Nano Letters |
| Publisher Date | 2018-08-01 |
| Access Restriction | Open |
| Rights Holder | © The Institution of Engineering and Technology |
| Subject Keyword | Abstraction Adsorption Adsorption And Desorption Kinetics Amorphous And Nanostructured Magnetic Materials Atom Transfer Biomedical Material Brilliant Cresyl Blue Chemical Exchanges Contact Time Disproportionate Drug Delivery System Drugs Dubinin-Radushkevich Equation Electrochemistry And Electrophoresis Elemental Analysis Enteric Drug Delivery Enteric Losartan Potassium Delivery Equilibrium Adsorption Data Evaporation And Condensation Exchange Parameter Fe2O3 Filled Polymers Fine-particle Magnetic System Fourier Transform Infrared Spectra Fourier Transform Infrared Spectroscopy Freundlich Equation Functionalised Sorbent Graft Polymer Infrared And Raman Spectra And Scattering (Condensed Matter) Ion Exchange Iron Compound Langmuir Analysis Losartan Potassium Loaded–modified MNPs Magnetic Nanoanion Exchanger Particle Magnetic Particle Magnetic Property of Nanostructure Magnetite NanoParticle Nanocomposite Nanofabrication Nanomagnetics Nanomedicine Nanoparticle Nanotechnology Application in Biomedicine Nanotube And Nanostructured Material Patient Care And Treatment PH Polymer Blends Polymeric NanoParticle Potassium Compound Redlich-Peterson Equation Sample PH Scanning Electron Microscopy Simulated Gastric Fluid Simulated Intestinal Fluid Sorption And Accommodation Coefficient Ssubstitution Structure of Solid Clusters Surface Chemistry Thermal Analysis Thermogravimetric Analysis Time 15.0 Hour Time 30.0 Hour Transmission Electron Microscopy |
| Content Type | Text |
| Resource Type | Article |
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