NDLI: Microfluidic switch for embryo and cell sorting

Content Provider	IEEE Xplore Digital Library
Author	Chen, C.C. Zappe, S. Sahin, O. Zhang, X.J. Furlong, E.E.M. Fish, M. Scott, M. Solgaard, O.
Copyright Year	2003
Description	Author affiliation: Stanford Univ., CA, USA (Chen, C.C.; Zappe, S.; Sahin, O.; Zhang, X.J.; Furlong, E.E.M.; Fish, M.; Scott, M.; Solgaard, O.)
Abstract	We present measurements and simulation of fluid flow and sphere motion in a pressure-driven microfluidic sorter designed for Drosophila embryos. We simulated the flow fields for different channel layouts and flow parameters to find geometries and conditions for optimised embryo movement. The microfluidic switch has a designed switching time of 360 /spl mu/s. We validated the sorter design with fluid experiments in devices fabricated from silicon and Pyrex wafers. The experimental and simulated results are compared both qualitatively and quantitatively by examining the concentration distribution of fluids. This type of microfluidic sorter is promising for micromanipulation of a variety of biological cells, and provides automated operations for higher throughput and accuracy.
Sponsorship	IEEE Electron Devices Soc
Starting Page	659
Ending Page	662
File Size	322782
Page Count	4
File Format	PDF
ISBN	0780377311
DOI	10.1109/SENSOR.2003.1215559
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2003-06-08
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Switches Microfluidics Embryo Sorting Fluid flow measurement Motion measurement Fluid flow Solid modeling Geometry Silicon
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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