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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Dalmay, C. Pothier, A. Cheray, M. Lalloué, F. Jauberteau, M.-O. Blondy, P. |
| Copyright Year | 2010 |
| Description | Author affiliation: XLIM - UMR 6172 Université de Limoges/CNRS, 87060, France (Dalmay, C.; Pothier, A.; Blondy, P.) || Homéostasie Cellulaire et Pathologies - EA 3842 Université de Limoges, 87025, France (Cheray, M.; Lalloué, F.; Jauberteau, M.-O.) |
| Abstract | An original label free bio detection method has been developed in order to discriminate biological samples at the cell scale. In this objective, highly sensitive resonant microwave biosensors have been designed in order to achieve analysis on very limited cells concentration. This paper demonstrates the potential of microwave frequencies for biological analysis using their ability to penetrate inside biological cells and probe their intracellular content without denaturation. Based on permittivity measurement in the 10 to 35 GHz range, the presented results illustrate that it is possible to use microwaves to discriminate biological cells in an non-invasive way as function of their differentiation degree. Application of this technique for stem cells identification appears as a very promising application and opens new areas in research for improving cancer treatments. |
| Starting Page | 620 |
| Ending Page | 623 |
| File Size | 1331553 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424460564 |
| ISSN | 0149645X |
| e-ISBN | 9781424460588 |
| e-ISBN | 9781424460571 |
| DOI | 10.1109/MWSYM.2010.5514663 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2010-05-23 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Microwave sensors Stem cells Biological cells Cells (biology) Resonance Biosensors Microwave frequencies Probes Permittivity measurement Cancer permittivity measurements biosensors electromagnetic fields microwave resonators |
| Content Type | Text |
| Resource Type | Article |
| Subject | Condensed Matter Physics Electrical and Electronic Engineering Radiation |
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