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Content Provider | IEEE Xplore Digital Library |
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Author | Krishnamoorthy, S. Vaska, P. Stoll, S. Purschke, M. Pratte, J.-F. Woody, C.L. Schlyer, D.J. O'Connor, P. |
Copyright Year | 2005 |
Description | Author affiliation: Dept. of Biomed. Eng., Stony Brook Univ., NY (Krishnamoorthy, S.) |
Abstract | Spatial resolution in positron emission tomography has steadily improved over the years, but remains substantially worse than in other imaging modalities, currently at ~2 mm for the most popular commercial tomographs. This is a serious limitation particularly for imaging mice, which have great potential in preclinical PET research because of their compatibility with genetic manipulation. A novel gamma-ray detector design which can achieve high resolution and sensitivity and also facilitates depth of interaction measurement has been developed. It consists of a slab of LSO and arrays of large-area avalanche photodiodes (APDs) on both sides which are used in a light sharing (Anger-type) scheme. A fully instrumented prototype detector has been constructed comprising a 10 mm thick LSO crystal and an array of 7 square APDs (each 11 mmtimes11 mm in area) optically coupled to each side. Preliminary measurements carried with a collimated source mounted on a computer controlled X-Y translational stage demonstrate a resolution of ~2.5 mm FWHM between the center of two APDs. Optimization of electronics noise factors is critical to improving detector performance |
Starting Page | 2845 |
Ending Page | 2848 |
File Size | 636759 |
Page Count | 4 |
File Format | |
ISBN | 0780392213 |
ISSN | 10957863 |
DOI | 10.1109/NSSMIC.2005.1596925 |
Language | English |
Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Publisher Date | 2005-10-23 |
Publisher Place | Puerto Rico |
Access Restriction | Subscribed |
Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
Subject Keyword | Prototypes Detectors Positron emission tomography Optical arrays High-resolution imaging Optical imaging Optical noise Spatial resolution Mice Genetics |
Content Type | Text |
Resource Type | Article |
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