NDLI: Impact of attenuation, scatter and depth dependent collimator response correction in 3-D cardiac SPECT imaging: a Monte Carlo investigation

Content Provider	IEEE Xplore Digital Library
Author	Tianyu Ma Yongjie Jin
Copyright Year	2004
Description	Author affiliation: Dept. of Eng. Phys., Tsinghua Univ., Beijing, China (Tianyu Ma; Yongjie Jin)
Abstract	Cardiac SPECT images are degraded by several physical effects, including attenuation, Compton scatter and collimator geometric response. We proposed a method, analytical SPECT modeling (ASM), for efficiently and accurately modeling the spatially varying SPECT point response function in nonuniform attenuating objects. A quasi Monte Carlo integration method was employed in the model, which resulted in an 1 to 2 orders of magnitude speed up in modeling process. Monte Carlo studies were done on simulated heart images from the NCAT phantom, and our model was implemented in a 3-D OSEM algorithm. The system transition matrix was generated based on the patient-specific attenuation map before reconstruction, which included several parts: 1) the primary matrix which modeled depth dependent collimator response of primary photons; 2) the attenuation factor matrix which modeled nonuniform attenuation of primary photons; 3) the scattering matrix which modeled attenuation, scatter and collimator response of scattered photons. An unmatched projector/backprojector was used to accelerate the reconstruction. Reconstruction results in which different degrading effects were modeled were compared in terms of global quantitative accuracy, contrast and noise level. Results showed that the more complete the degrading effects were modeled in reconstruction, the higher quality and quantitative accuracy could be obtained.
Starting Page	3594
Ending Page	3598
File Size	1231541
Page Count	5
File Format	PDF
ISBN	0780387007
ISSN	10823654
e-ISBN	0780387015
DOI	10.1109/NSSMIC.2004.1466661
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-10-16
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Attenuation Monte Carlo methods Electromagnetic scattering Particle scattering Image reconstruction Degradation Single photon emission computed tomography Optical collimators Analytical models Heart
Content Type	Text
Resource Type	Article

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