NDLI: Fast CT/SPECT derived 3D Monte Carlo dose computations for /sup 131/I internal emitter therapy

Content Provider	IEEE Xplore Digital Library
Author	Wilderman, S.J. Gunnett, R.B. Kearfott, K.J. Dewaraja, Y.K.
Copyright Year	2004
Description	Author affiliation: Dept. of Nucl. Eng. & Radiol. Sci., Michigan Univ., Ann Arbor, MI, USA (Wilderman, S.J.; Gunnett, R.B.; Kearfott, K.J.)
Abstract	The DPM (Dose Planning Method) Monte Carlo electron and photon transport program, designed for fast computation of radiation dose in external electron beam radiotherapy, has been adapted to the determination of dose in patient-specific I-131 internal emitter therapy. Because both its photon and electron transport mechanics algorithms have been optimized for computation in 3D voxelized geometries (in particular, those from CT scans), DPM is perfectly suited for patient-specific dose calculations in internal emitter therapy. The necessary inputs are a patient CT image, a registered SPECT image, and any number of registered masks defining regions of interest. DPM has been benchmarked for this application by comparing computed absorption fractions and self-absorption fractions for a variety of organs using a Zubal phantom with results from other Monte Carlo programs and reference results from the Medical Internal Radionuclide Dose (MIRD) Committee standards, and the sourcing and photon tracking algorithms of DPM have been further benchmarked by comparison to experimental data. This paper presents a description of the program, the results of the benchmark studies, and some sample computations using patient data from radioimmunotherapy studies.
Starting Page	3398
Ending Page	3401
File Size	607848
Page Count	4
File Format	PDF
ISBN	0780387007
ISSN	10823654
e-ISBN	0780387015
DOI	10.1109/NSSMIC.2004.1466616
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-10-16
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Monte Carlo methods Computed tomography Single photon emission computed tomography Optical computing Electron beams Electron emission Medical treatment Geometrical optics Computational geometry Computer applications
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in