NDLI: A-PET: a high sensitivity animal PET camera

Content Provider	IEEE Xplore Digital Library
Author	Surti, S. Karp, J.S. Perkins, A.E. Freifelder, R. Muehllehner, G.
Copyright Year	2003
Description	Author affiliation: Dept. of Radiol., Pennsylvania Univ., Philadelphia, PA, USA (Surti, S.; Karp, J.S.)
Abstract	In recent years it has been shown that PET is capable of obtaining in vivo metabolic images of small animals. These serve as models to study the development and progress of diseases within humans. Imaging small animals requires not only image resolution better than 2mm, but also high sensitivity in order to image ligands with low specific activity or radiochemical yields. Towards achieving these goals, we have developed a discrete 2 /spl times/ 2 /spl times/ 10mm/sup 3/ GSO Anger-logic detector for use in a high resolution, high sensitivity, and high count-rate animal PET scanner. This detector uses relatively large 19mm diameter photomultiplier tubes (PMT), but nevertheless achieves good crystal separation and energy resolution. The scanner (A-PET) has a port diameter of 21 cm, transverse field-of-view of 12.8 cm, axial length of 12.8 cm, and operates in 3D volume imaging mode. The absolute coincidence sensitivity is expected to be 2.3% for a point source. Due to the use of large PMTs in an Anger design, the encoding ratio (number of crystals/PMT) is high, which reduces the complexity and leads to a cost-effective scanner. Simulation results show that this scanner can achieve NEC rates significantly higher than many of the current generation of animal scanners for small cylindrical phantoms due to its high sensitivity and reduced deadtime. The scanner construction was recently completed and initial calibrations are currently in progress.
Starting Page	1056
Ending Page	1060
File Size	1146527
Page Count	5
File Format	PDF
ISBN	0780376366
DOI	10.1109/NSSMIC.2002.1239504
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-11-10
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Animals Positron emission tomography Cameras High-resolution imaging Detectors Energy resolution In vivo Diseases Humans Image resolution
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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