NDLI: Oriented and Vectorial Patterning of Cardiac Myocytes Using a Microfluidic Dielectrophoresis Chip - Towards Engineered Cardiac Tissue with Controlled Macroscopic Anisotropy

Content Provider	IEEE Xplore Digital Library
Author	Yang, M. Lim, C.C. Liao, R. Zhang, X.
Copyright Year	2006
Description	Author affiliation: Boston University, Boston, Massachusetts, USA (Yang, M.)
Abstract	Recently, the ability to create engineered heart tissues with a preferential cell orientation has gained much interest. Here, we present a novel method to construct a cardiac myocyte tissue-like structure using a combination of dielectrophoresis and electro-orientation via a microfluidic chip. Using the interdigitated-castellated microelectrodes, the induction of a mutually attractive dielectrophoretic force between cardiac myocytes can lead the cells moving close to each other and forming a tissue-like structure with orientation along the AC electric field between the electrode gaps. Both experimental results and theoretical analysis have indicated that a large orientation torque and force can be achieved by choosing an optimal frequency and decreasing the conductivity of the medium to a low level, where the orientation torque weakly depends on the frequency. In this paper, electromechanical experiments were performed to demonstrate the structural and functional anisotropy of the electro-oriented structure.
Starting Page	8
Ending Page	11
File Size	802814
Page Count	4
File Format	PDF
ISBN	0780394755
ISSN	10846999
DOI	10.1109/MEMSYS.2006.1627723
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2006-01-22
Publisher Place	Turkey
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Microfluidics Dielectrophoresis Cardiac tissue Anisotropic magnetoresistance Torque Frequency Heart Microelectrodes Electric fields Electrodes
Content Type	Text
Resource Type	Article
Subject	Condensed Matter Physics Electronic, Optical and Magnetic Materials Mechanical Engineering Electrical and Electronic Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Oriented and Vectorial Patterning of Cardiac Myocytes Using a Microfluidic Dielectrophoresis Chip—Towards Engineered Cardiac Tissue With Controlled Macroscopic Anisotropy

Off-chip electrode insulator based dielectrophoresis

Numerical study of induced electric field in a microfluidic system for cell electroporation

Sequential Field-Flow Cell Separation Method in a Dielectrophoretic Chip With 3-D Electrodes

Electronic-microfluidic system for sorting particles and whole blood using gel electrodes

Working towards a sample preparation device with carbon nanotubes

Optimization of microfluidic particle sorters based on dielectrophoresis

Basic theory of dielectrophoresis and electrorotation

In-Vitro Rapid Centimeter-Scale Reconstruction of Lobule-Mimetic Liver Tissue Employing Dielectrophoresis-Based Cell Patterning

Oriented and Vectorial Patterning of Cardiac Myocytes Using a Microfluidic Dielectrophoresis Chip - Towards Engineered Cardiac Tissue with Controlled Macroscopic Anisotropy

Similar Documents

Oriented and Vectorial Patterning of Cardiac Myocytes Using a Microfluidic Dielectrophoresis Chip—Towards Engineered Cardiac Tissue With Controlled Macroscopic Anisotropy

Off-chip electrode insulator based dielectrophoresis

Numerical study of induced electric field in a microfluidic system for cell electroporation

Sequential Field-Flow Cell Separation Method in a Dielectrophoretic Chip With 3-D Electrodes

Electronic-microfluidic system for sorting particles and whole blood using gel electrodes

Working towards a sample preparation device with carbon nanotubes

Optimization of microfluidic particle sorters based on dielectrophoresis

Basic theory of dielectrophoresis and electrorotation

In-Vitro Rapid Centimeter-Scale Reconstruction of Lobule-Mimetic Liver Tissue Employing Dielectrophoresis-Based Cell Patterning

Oriented and Vectorial Patterning of Cardiac Myocytes Using a Microfluidic Dielectrophoresis Chip - Towards Engineered Cardiac Tissue with Controlled Macroscopic Anisotropy