NDLI: Profile of autonomic cardiac control in patients who are not considered ready for weaning from mechanical ventilation

Content Provider	IEEE Xplore Digital Library
Author	Matveev, M. Krasteva, V. Jekova, I. Georgiev, G. Milanov, S. Prokopova, R. Todorova, L.
Copyright Year	2012
Description	Author affiliation: University Emergency Hospital "Pirogov", Sofia, Bulgaria (Georgiev, G.; Milanov, S.) \|\| Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria (Matveev, M.; Krasteva, V.; Jekova, I.; Todorova, L.) \|\| University Multiprofile Hospital for Active Treatment "Saint Anna", Sofia, Bulgaria (Prokopova, R.)
Abstract	This study tracks the global tendency of the heart rate variability (HRV) profile over five ventilation modes, aiming to find evidences on the hypothesis that patients who failed during the weaning process manifest important differences in the autonomic nervous system activity. This preliminary study enrols 17 patients (7 successful (S), 10 failure (F)) who underwent weaning with AVEA ventilator. Time- and frequency- domain HRV analysis is applied over 5-min ECG episodes recorded at the beginning of 5 ventilation modes: (1) controlled mechanical ventilation (CMV) on a sedated patient; (2) CMV on a sedated and paralyzed patient; (3) Pressure support ventilation with zero back-up pressure PSV(0); (4) PSV at 12–25 cmH2O; (5) Spontaneous breathing trial (SBT) at 8 cmH2O. Our results support the finding of other authors that during SBT, the patients who succeed in weaning show a prevalently sympathetic modulation, while relatively increased vagal activity is typical for the F-group. PSV(0) is however an outstanding test for which F-patients manifest about 3 to 20 fold increased sympathetic and vagal activity compared to the S-group.
Starting Page	625
Ending Page	628
File Size	297932
Page Count	4
File Format	PDF
ISBN	9781467320764
ISSN	2325887X
e-ISBN	9781467320771
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-09-09
Publisher Place	Poland
Access Restriction	Subscribed
Rights Holder	Creative Commons Attribution License 2.5 (CCAL)
Subject Keyword	Ventilation Heart rate variability Time frequency analysis Standards Resonant frequency Hemodynamics
Content Type	Text
Resource Type	Article
Subject	Computer Science Cardiology and Cardiovascular Medicine

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