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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Vidal, C. Beggs, D. Younes, L. Jain, S.K. Jedynak, B. |
| Copyright Year | 2011 |
| Description | Author affiliation: Center for Imaging Science, Johns Hopkins University School of Medicine, USA (Younes, L.; Jedynak, B.) || Center for Tuberculosis Research, Johns Hopkins University School of Medicine, USA (Jain, S.K.) || Dept. of Applied Mathematics and Statistics, Johns Hopkins University, USA (Beggs, D.) || Division of Imaging and Applied Mathematics, CDRH, Food and Drug Administration, Johns Hopkins University School of Medicine, USA (Vidal, C.) |
| Abstract | We present a simple and elegant method to incorporate user input in a template-based segmentation method for diseased organs. The user provides a partial segmentation of the organ of interest, which is used to guide the template towards its target. The user also highlights some elements of the background that should be excluded from the final segmentation. We derive by likelihood maximization a registration algorithm from a simple statistical image model in which the user labels are modeled as Bernoulli random variables. The resulting registration algorithm minimizes the sum of square differences between the binary template and the user labels, while preventing the template from shrinking, and penalizing for the inclusion of background elements into the final segmentation. We assess the performance of the proposed algorithm on synthetic images in which the amount of user annotation is controlled. We demonstrate our algorithm on the segmentation of the lungs of Mycobacterium tuberculosis infected mice from μCT images. |
| Starting Page | 1434 |
| Ending Page | 1437 |
| File Size | 156476 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424441273 |
| ISSN | 19457928 |
| DOI | 10.1109/ISBI.2011.5872669 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2011-03-30 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Image segmentation Lungs Computed tomography Lesions Mice Shape Diseased Organs Registration Template-based Segmentation User Input |
| Content Type | Text |
| Resource Type | Article |
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