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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Ardekani, S. Weiss, R.G. Lardo, A.C. George, R.T. Lima, J.A.C. Wu, K.C. Miller, M.I. Winslow, R.L. Younes, L. |
| Copyright Year | 2009 |
| Description | Author affiliation: Division of Cardiology, Johns Hopkins University Medical Institutions, Baltimore, MD, USA (Weiss, R.G.; Lardo, A.C.; George, R.T.; Lima, J.A.C.; Wu, K.C.) || Institute for computational Medicine, Johns Hopkins University, Baltimore, MD, USA (Ardekani, S.; Winslow, R.L.) || Center for Imaging Sciences, Johns Hopkins University, Baltimore, MD, USA (Miller, M.I.; Younes, L.) |
| Abstract | In this study, we used multi-detector computed tomographic (MDCT) images of human left ventricles at end-diastole and end-systole to perform quantitative analysis and comparison of heart motion in patients with anterior wall myocardial infarction and ischemic cardiomyopathy (ICM) versus those with global non-ischemic cardiomyopathy (NICM). MDCT ventricular images of 25 patients (13 with ICM) with ejection fraction (EF) ≪ 35% were analyzed. We used a novel technique (parallel transport) to translate within subject motion-related end-diastole to end-systole deformation to a common coordinate system without incorporating across-subject variation. We then performed a hypothesis testing on the ventricular motion variation in the global template coordinate. Statistical analysis indicated that there were meaningful ventricular motion differences between ICM and NICM groups. Additionally, patients with ICM demonstrated less wall thickening at ES in the anterior wall where the pathology was located. |
| Starting Page | 899 |
| Ending Page | 902 |
| File Size | 287603 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424439317 |
| ISSN | 19457928 |
| DOI | 10.1109/ISBI.2009.5193198 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2009-06-28 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Motion analysis Cardiology Image analysis Tomography Humans Image motion analysis Performance analysis Heart Myocardium Performance evaluation cardiomyopathy parallel transport cardiac motion analysis |
| Content Type | Text |
| Resource Type | Article |
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