NDLI: NECR analysis of 3D brain PET scanner designs

Content Provider	IEEE Xplore Digital Library
Author	Stearns, C.W. Cherry, S.R. Thompson, C.J.
Copyright Year	1963
Abstract	A dedicated 3D brain PET scanner has several advantages, most notably increased sensitivity, over a whole body scanner for neurological studies. However, brain scanners have higher scatter fractions, random count-rates and deadtime for the same activity concentration. We have used noise effective count-rate (NECR) analysis to compare brain scanners of 53, 60, and 66 cm diameter with the GE ADVANCE whole body scanner (93 cm diameter). Monte Carlo simulations of a brain-sized phantom (16 cm diameter, 13 cm length) in the ADVANCE geometry were used to develop a model for NECR performance, which was reconciled to results from a decay series measurement. The model was then used to predict the performance of the brain scanner designs. The brain scanners have noise effective sensitivities (the slope of the NECR curve at zero activity) as much as 40% higher than the body scanner. However, their NECR advantage diminishes quickly as the activity concentration increases. The brain scanners' NECR equals the body scanner with about 0.7-0.8 mCi in the phantom; the body scanner has superior NECR performance at higher activity levels. An imaging center concentrating on only very low activity imaging tasks would find the efficiency advantage of a smaller detector diameter valuable, while a center performing higher activity studies such as bolus water injections or 5 mCi FDG injections might prefer the count rate performance of a whole body scanner.<>
Sponsorship	IEEE Nuclear and Plasma Sciences Society Computer Applications in Nuclear and Plasma Sciences (CANPS) Lawrence Berkeley Lab. Lawrence Livermore Nat. Lab. APS College of William and Mary Continuous Electron Beam Accelerator Facility NASA Defence Nuclear Agency Sandia National Laboratories Jet Propulsion Laboratory Brookhaven Nat. Lab. Lawrence Livermore Nat. Lab IEEE/NPPS Radiat. Effects Committee Defence Nuclear Agency/DoD Sandia National Laboratories/DOE Jet Propulsion Laboratory/NASA Phillips Lab./DoD
Starting Page	1075
Ending Page	1079
Page Count	5
File Size	405176
File Format	PDF
ISSN	00189499
Volume Number	42
Issue Number	4
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1995-08-01
Publisher Place	U.S.A.
Access Restriction	One Nation One Subscription (ONOS)
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Whole-body PET Imaging phantoms Brain modeling Scattering Geometry Solid modeling Length measurement Predictive models Detectors
Content Type	Text
Resource Type	Article
Subject	Nuclear and High Energy Physics Electrical and Electronic Engineering Nuclear Energy and Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

NECR analysis of 3D brain PET scanner designs

A whole body phantom for 3D PET

Triple energy window scatter correction technique in PET

A Monte Carlo model of noise components in 3D PET

Performance of a high sensitivity PET scanner based on LSO panel detectors

Evaluation of attenuation correction methodology in the allegro PET system

Self normalization for continuous 3D whole body emission data in 3D PET

A High-Sensitivity Small-Animal PET Scanner: Development and Initial Performance Measurements

A phantom comparison study for measuring PEM scanner sensitivity

NECR analysis of 3D brain PET scanner designs

Similar Documents

NECR analysis of 3D brain PET scanner designs

A whole body phantom for 3D PET

Triple energy window scatter correction technique in PET

A Monte Carlo model of noise components in 3D PET

Performance of a high sensitivity PET scanner based on LSO panel detectors

Evaluation of attenuation correction methodology in the allegro PET system

Self normalization for continuous 3D whole body emission data in 3D PET

A High-Sensitivity Small-Animal PET Scanner: Development and Initial Performance Measurements

A phantom comparison study for measuring PEM scanner sensitivity

NECR analysis of 3D brain PET scanner designs