NDLI: Fixation-free assessment of the Hirschberg ratio.

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Fixation-free assessment of the Hirschberg ratio.

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Fixation-free assessment of the Hirschberg ratio.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Model, Dmitri Sturm, Veit Eizenman, Moshe
Description	Country affiliation: Canada Author Affiliation: Model D ( Department of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario, Canada.)
Abstract	PURPOSE: To describe a novel methodology by which to measure the Hirschberg ratio (HR) in infants. The methodology does not require fixation on specific points, and measurements are made while infants look naturally at a display. METHODS: The HR is calculated automatically from measurements of the direction of the optical axis, the position of the pupil center, and corneal reflexes in video images from an advanced two-camera eye-tracking system. The performance of the novel fixation-free procedure (FFP) was evaluated in 43 adults by measuring the average difference and the 95% limits of agreement with the standard fixation-based procedure (FBP). Repeatability of the HR measurements was evaluated by assessing the 95% limits of agreement between two independent measurements. Performance of the FFP was also evaluated in five infants. RESULTS: In adults, the average HR was 12.89 +/- 1.22 degrees/mm for FFP and 12.81 +/- 1.22 degrees/mm for FBP. FFP and FBP measurements were highly correlated (r = 0.95; P < 0.001). The 95% limits of agreement between FFP and FBP were +/-0.86 degrees/mm. The 95% limits of agreement of repeated measurements were +/-0.66 degrees/mm for FFP and +/-0.77 degrees/mm for FBP. In infants, the 95% limits of agreement of repeated measurements by FFP were +/-0.63 degrees/mm. CONCLUSIONS: In adults, the FFP provides accurate measurements of the HR that are in excellent agreement with measurements by FBP. In infants, measurements of HR by FFP show the same repeatability and consistency.
ISSN	01460404
e-ISSN	15525783
Journal	Investigative Opthalmology & Visual Science
Issue Number	8
Volume Number	51
Language	English
Publisher	Association for Research in Vision and Ophthalmology
Publisher Date	2010-08-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Diagnostic Techniques, Ophthalmological Fixation, Ocular Physiology Vision, Binocular Adolescent Blinking Eye Movements Infant Video Recording Research Support, Non-u.s. Gov't Discipline Ophthalmology
Content Type	Text
Resource Type	Article
Subject	Ophthalmology Sensory Systems Cellular and Molecular Neuroscience

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