NDLI: Histamine involvement in visual development and adaptation.

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Upregulation of retinal neuronal MCP-1 in the rodent model of diabetic retinopathy and its function in vitro.

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Notch inhibition during corneal epithelial wound healing promotes migration.

Effects of strabismic amblyopia and strabismus without amblyopia on visuomotor behavior, I: saccadic eye movements.

High prevalence of myopia and high myopia in 5060 Chinese university students in Shanghai.

Automated segmentation of the choroid from clinical SD-OCT.

Histamine involvement in visual development and adaptation.

Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study.

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Structure-function relationship between FDF, FDT, SAP, and scanning laser ophthalmoscopy in glaucoma patients.

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Bevacizumab and rapamycin can decrease corneal opacity and apoptotic keratocyte number following photorefractive keratectomy.

Dose-ranging evaluation of intravitreal siRNA PF-04523655 for diabetic macular edema (the DEGAS study).

The role of VIP in cornea.

Induction of Endoplasmic Reticulum Stress Genes, BiP and Chop, in Genetic and Environmental Models of Retinal Degeneration

Relationship between retinal layer thickness and the visual field in early age-related macular degeneration.

The epidemiology and incidence of cytomegalovirus retinitis in the HIV population in Singapore over 6 years.

Improved reproducibility in measuring the laminar thickness on enhanced depth imaging SD-OCT images using maximum intensity projection.

Visual acuity, crowding, and stereo-vision are linked in children with and without amblyopia.

A novel role of complement in retinal degeneration.

Protective effect of carnosic acid, a pro-electrophilic compound, in models of oxidative stress and light-induced retinal degeneration.

Expression and role of VEGF--a in the ciliary body.

Role of hepatocyte growth factor in promoting the growth of human corneal endothelial cells stimulated by L-ascorbic acid 2-phosphate.

Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB.

Association between choroidal thickness and ocular perfusion pressure in young, healthy subjects: enhanced depth imaging optical coherence tomography study.

The IS/OS junction layer in the natural history of type 2 idiopathic macular telangiectasia.

Macular choroidal thickness measured by swept source optical coherence tomography in eyes with inferior posterior staphyloma.

Posture-induced intraocular pressure changes in eyes with open-angle glaucoma, primary angle closure with or without glaucoma medications, and control eyes.

Development-related splicing regulates pituitary adenylate cyclase-activating polypeptide (PACAP) receptors in the retina.

Keratitis-associated fungi form biofilms with reduced antifungal drug susceptibility.

Anti-angiogenic effect of luteolin on retinal neovascularization via blockade of reactive oxygen species production.

Aligning scan locations from consecutive spectral-domain optical coherence tomography examinations: a comparison among different strategies.

Pulsatile movement of the optic nerve head and the peripapillary retina in normal subjects and in glaucoma.

Retinal prosthesis safety: alterations in microglia morphology due to thermal damage and retinal implant contact.

Axonal protection via modulation of the amyloidogenic pathway in tumor necrosis factor-induced optic neuropathy.

Relaxin 2 is functional at the ocular surface and promotes corneal wound healing.

Education is positively associated with macular pigment: the Irish Longitudinal Study on Ageing (TILDA).

Repeatability of Spectralis OCT measurements of macular thickness and volume in diabetic macular edema.

Validating a nonhuman primate model of super-selective intraophthalmic artery chemotherapy: comparing ophthalmic artery diameters.

Long-term decline of central cone function in retinitis pigmentosa evaluated by focal electroretinogram.

Dynamic contrast-enhanced MRI for assessing therapeutic response of choroidal neovascularization in a rat model.

Relationship between orbital optic nerve axon counts and retinal nerve fiber layer thickness measured by spectral domain optical coherence tomography.

Metallothionein-III deficiency exacerbates light-induced retinal degeneration.

The impact of macular pigment augmentation on visual performance using different carotenoid formulations.

Ectopic epithelial implants following surface ablation of the cornea.

Short-term effects of extremely low frequency pulsed electromagnetic field on corneas with alkaline burns in rabbits.

The choroid is thicker in angle closure than in open angle and control eyes.

In vitro effects of bevacizumab treatment on newborn rat retinal cell proliferation, death, and differentiation.

Author response: Different efficacy of propranolol in mice with oxygen-induced retinopathy: could differential effects of propranolol be related to differences in mouse strains?

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Histamine involvement in visual development and adaptation.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Dalla, Christina Tiligada, Ekaterini Daifoti, Zeta Papadopoulou Bessinis, Dimitrios P.
Description	Country affiliation: Greece Author Affiliation: Bessinis DP ( Department of Pharmacology, Medical School, University of Athens, Athens, Greece.)
Abstract	PURPOSE: This study evaluated the level of histamine in the interaction between the environment and the visual system during lifespan development, exploring potential sex differences. METHODS: Male and female Wistar rats, reared in standard laboratory or enriched-environment cages from birth to prepuberty or adulthood, were sacrificed during the critical period for visual development at postnatal day (P) 25 (P25) or in adulthood at P90. Additionally, animals born in standard conditions were exposed to an enriched environment at P90 and sacrificed at P150. The optic chiasm and the visual cortex were dissected out and tissue histamine was quantified fluorophotometrically. Statistical analyses were performed by ANOVA. RESULTS: Histamine levels in the optic chiasm were higher in male than in female rats at all ages. Comparable sex differences in the visual cortex were observed only during prepuberty. Basal histamine content in the optic chiasm was higher in prepuberty and decreased in adulthood in a sex-independent manner. Exposure to an enriched environment decreased optic chiasm histamine levels in both sexes and resulted in no sex difference in the cortical histamine levels at any age. Increased amine levels were detected in the optic chiasm of female rats exposed to an enriched environment during adulthood. CONCLUSIONS: This study presents first evidence associating central histamine levels with the visual system development and environmental adaptation, thus providing the lead for the investigation of the hitherto elusive role of histamine in the regulation of visual processes. Furthermore, the findings challenge the impact of laboratory animal raising environments in developmental and behavioral studies.
ISSN	01460404
e-ISSN	15525783
Journal	Investigative Opthalmology & Visual Science
Issue Number	12
Volume Number	53
Language	English
Publisher	Association for Research in Vision and Ophthalmology
Publisher Date	2012-11-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Adaptation, Physiological Physiology Histamine Metabolism Models, Neurological Optic Chiasm Growth & Development Visual Cortex Animals Rats, Wistar Comparative Study Research Support, Non-u.s. Gov't Discipline Ophthalmology
Content Type	Text
Resource Type	Article
Subject	Ophthalmology Sensory Systems Cellular and Molecular Neuroscience

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