NDLI: Developmental plasticity of CNS microglia.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2001 Volume: 98 Issue: 26

Year: 2001 Volume: 98 Issue: 25

Year: 2001 Volume: 98 Issue: 24

Year: 2001 Volume: 98 Issue: 23

Year: 2001 Volume: 98 Issue: 22

Year: 2001 Volume: 98 Issue: 21

Year: 2001 Volume: 98 Issue: 20

Year: 2001 Volume: 98 Issue: 19

Year: 2001 Volume: 98 Issue: 18

Year: 2001 Volume: 98 Issue: 17

Year: 2001 Volume: 98 Issue: 16

Year: 2001 Volume: 98 Issue: 15

Year: 2001 Volume: 98 Issue: 14

Year: 2001 Volume: 98 Issue: 13

Year: 2001 Volume: 98 Issue: 12

Year: 2001 Volume: 98 Issue: 11

Glutamate antagonists limit tumor growth

Tomato Ve disease resistance genes encode cell surface-like receptors.

Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation

Top-down free-energy minimization on protein potential energy landscapes.

Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching.

Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.

Requirement of the nicotinic acetylcholine receptor beta 2 subunit for the anatomical and functional development of the visual system.

Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization.

Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging.

Diffractive optics-based heterodyne-detected four-wave mixing signals of protein motion: from 'protein quakes' to ligand escape for myoglobin.

Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair.

Measuring the diaspora for virus-specific CD8+ T cells.

Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation?

Altered stability of pulmonary surfactant in SP-C-deficient mice.

Large vortex-like structure of dipole field in computer models of liquid water and dipole-bridge between biomolecules.

Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia.

Evidence in support of a four transmembrane-pore-transmembrane topology model for the Arabidopsis thaliana $Na^{+}/K^{+}$ translocating AtHKT1 protein, a member of the superfamily of $K^{+}$ transporters

Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF.

Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.

Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway.

Antiviral activities of the soluble extracellular domains of type I interferon receptors.

Changes in the prevalence of chronic disability in the United States black and nonblack population above age 65 from 1982 to 1999.

BimD/SPO76 is at the interface of cell cycle progression, chromosome morphogenesis, and recombination

Using electroactive substrates to pattern the attachment of two different cell populations.

Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets.

An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus.

Desert dust suppressing precipitation: a possible desertification feedback loop.

CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice.

Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor.

A dendrodendritic reciprocal synapse provides a recurrent excitatory connection in the olfactory bulb.

Strong DNA binding by covalently linked dimeric Lac headpiece: evidence for the crucial role of the hinge helices.

Horizontal transfer of oncogenes by uptake of apoptotic bodies.

Identification of multiple quantitative trait loci linked to prion disease incubation period in mice

Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo.

Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members.

The evolution of coloration and toxicity in the poison frog family (Dendrobatidae).

Oncolytic herpes simplex virus vector with enhanced MHC class I presentation and tumor cell killing.

Stimulation via CD40 can substitute for CD4 T cell function in preventing reactivation of a latent herpesvirus.

Removing symbiotic Wolbachia bacteria specifically inhibits oogenesis in a parasitic wasp.

Point mutations in a nucleoside transporter gene from Leishmania donovani confer drug resistance and alter substrate selectivity.

Conformational coupling in the chemotaxis response regulator CheY.

Generalized transduction in Streptomyces coelicolor.

In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies.

A type IB topoisomerase with DNA repair activities.

Diazepam-induced changes in sleep: role of the alpha 1 GABA(A) receptor subtype.

Insect herbivory, plant defense, and early Cenozoic climate change.

Maintenance of caspase-3 proenzyme dormancy by an intrinsic 'safety catch' regulatory tripeptide.

Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

Direct DNA binding by Brca1.

Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator.

Mechanical stress is communicated between different cell types to elicit matrix remodeling.

RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage.

Biomechanics of the movable pretarsal adhesive organ in ants and bees.

Trypanosoma brucei CTP synthetase: a target for the treatment of African sleeping sickness.

Arg-302 facilitates deprotonation of Glu-325 in the transport mechanism of the lactose permease from Escherichia coli

Refractoriness to melatonin occurs independently at multiple brain sites in Siberian hamsters.

Designing surfaces that kill bacteria on contact.

Effects of sampling standardization on estimates of Phanerozoic marine diversification.

Analysis of gene expression during myc oncogene-induced lymphomagenesis in the bursa of Fabricius.

Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release.

Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons.

Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes.

Desmuslin, an intermediate filament protein that interacts with alpha -dystrobrevin and desmin.

DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature

The pKa of His-24 in the folding transition state of apomyoglobin.

CtBP-dependent activities of the short-range Giant repressor in the Drosophila embryo.

Quantification of the hydrophobic interaction by simulations of the aggregation of small hydrophobic solutes in water.

T cell-specific FADD-deficient mice: FADD is required for early T cell development.

Negative frequency-dependent selection maintains a dramatic flower color polymorphism in the rewardless orchid Dactylorhiza sambucina (L.) Soo.

Three-dimensional reconstruction of the recombinant type 3 ryanodine receptor and localization of its amino terminus

A DAF-1-binding protein BRA-1 is a negative regulator of DAF-7 TGF-beta signaling.

Sense- and antisense-mediated gene silencing in tobacco is inhibited by the same viral suppressors and is associated with accumulation of small RNAs.

An important role of an inducible RNA-dependent RNA polymerase in plant antiviral defense.

Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying $K^{+}$ channels

Integrated fossil and molecular data reconstruct bat echolocation.

Painting of fourth, a chromosome-specific protein in Drosophila.

CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.

Rapid, local adaptation of zooplankton behavior to changes in predation pressure in the absence of neutral genetic changes.

Nondestructive, in situ, cellular-scale mapping of elemental abundances including organic carbon in permineralized fossils.

The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan.

Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.

The arginine finger of RasGAP helps Gln-61 align the nucleophilic water in GAP-stimulated hydrolysis of GTP

Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45.

Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus.

Crystal cataracts: human genetic cataract caused by protein crystallization.

Regulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1.

Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility.

c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity.

Evolution of genome-phenome diversity under environmental stress.

Developmental plasticity of CNS microglia.

T cell activation up-regulates cyclic nucleotide phosphodiesterases 8A1 and 7A3.

A role for estrogen receptor beta in the regulation of growth of the ventral prostate.

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.

Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors.

A missense mutation of the $Na^{+}$ channel $α_{II}$ subunit gene $Na_{v}1.2$ in a patient with febrile and afebrile seizures causes channel dysfunction

Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells.

Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity.

Induction of male sterility in plants by metabolic engineering of the carbohydrate supply.

Stable isotope evidence for increasing dietary breadth in the European mid-Upper Paleolithic.

Year: 2001 Volume: 98 Issue: 10

Year: 2001 Volume: 98 Issue: 9

Year: 2001 Volume: 98 Issue: 8

Year: 2001 Volume: 98 Issue: 7

Year: 2001 Volume: 98 Issue: 6

Year: 2001 Volume: 98 Issue: 5

Year: 2001 Volume: 98 Issue: 4

Year: 2001 Volume: 98 Issue: 3

Year: 2001 Volume: 98 Issue: 2

Year: 2001 Volume: 98 Issue: 1

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Developmental plasticity of CNS microglia.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Stern, L. J. Belyanskaya, S. L. Fischer, F. R. Cipriani, B. Ricciardi-castagnoli, P. Strominger, J. L. Santambrogio, L. Brosnan, C. F. Riese, R.
Description	Author Affiliation: Santambrogio L ( Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA 02115, USA. laura_santambrogio@dfci.harvard.edu);
Abstract	Microglia arise from CD45(+) bone marrow precursors that colonize the fetal brain and play a key role in central nervous system inflammatory conditions. We report that parenchymal microglia are uncommitted myeloid progenitors of immature dendritic cells and macrophages by several criteria, including surface expression of 'empty' class II MHC protein and their cysteine protease (cathepsin) profile. Microglia express receptors for stem cell factor and can be skewed toward more dendritic cell or macrophage-like profiles in response to the lineage growth factors granulocyte/macrophage colony-stimulating factor or macrophage colony-stimulating factor. Thus, in contrast to other organs, where terminally differentiated populations of resident dendritic cells and/or macrophages outnumber colonizing precursors, the majority of microglia within the brain remain in an undifferentiated state.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	11
Volume Number	98
Language	English
Publisher	National Academy of Sciences
Publisher Date	2001-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Microglia Immunology Neuronal Plasticity Animals Cathepsins Genetics Cell Differentiation Cells, Cultured Central Nervous System Cytology Dendritic Cells Granulocyte-Macrophage Colony-Stimulating Factor Pharmacology Hematopoietic Stem Cells Histocompatibility Antigens Class II Interferon-gamma Macrophages Membrane Proteins Biosynthesis Mice Drug Effects Stem Cell Factor Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in