NDLI: Effect of Cu content on the antibacterial activity of titanium-copper sintered alloys.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Liu, Jie Li, Fangbing Liu, Cong Wang, Hongying Ren, Baorui Yang, Ke Zhang, Erlin
Description	Author Affiliation: Liu J ( Jiamusi University, Jiamusi 154007, PR China); Li F ( Jiamusi University, Jiamusi 154007, PR China.); Liu C ( Jiamusi University, Jiamusi 154007, PR China.); Wang H ( Jiamusi University, Jiamusi 154007, PR China.); Ren B ( Jiamusi University, Jiamusi 154007, PR China.); Yang K ( Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, PR China.); Zhang E ( Jiamusi University, Jiamusi 154007, PR China)
Abstract	The phase constitution and the microstructure Ti-x Cu (x=2, 5, 10 and 25 wt.%) sintered alloys were investigated by XRD and SEM and the antibacterial activity was assessed in order to investigate the effect of the Cu content on the antibacterial activity. The results have shown that Ti2Cu was synthesized as a main secondary phase in all Ti-Cu alloys while Cu-rich phase was formed in the alloys with 5 wt.% or more copper. Antibacterial tests have showed that the Cu content influences the antibacterial rate seriously and only the alloys with 5 wt.% or high Cu have a strong and stable antibacterial rate, which indicates that the Cu content in Ti-Cu alloys must be at least 5 wt.% to obtain strong and stable antibacterial property. The Cu content also influenced the Cu ion release behavior. High Cu ion release concentration and high Cu ion release rate were observed for Ti-Cu alloys with high Cu content. It was concluded that the Cu content affects the Cu existence and the Cu ion release behavior, which in turn influences the antibacterial property. It was thought that the Cu-rich phase should play an important role in the strong antibacterial activity.
File Format	HTM / HTML
ISSN	09284931
Volume Number	35
e-ISSN	18730191
Journal	Materials Science and Engineering: C
Language	English
Publisher	Elsevier
Publisher Date	2014-02-01
Publisher Place	Netherlands
Access Restriction	Subscribed
Subject Keyword	Discipline Materials Science Bacterial Physiological Phenomena Drug Effects Biocompatible Materials Pharmacology Copper Chemistry Titanium Alloys Anti-bacterial Agents Chemical Synthesis Cell Survival Compressive Strength Hardness Hot Temperature Materials Testing Surface Properties Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Mechanics of Materials Biomaterials Condensed Matter Physics Bioengineering Mechanical Engineering

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