NDLI: Antimicrobial hyperbranched poly(ester amide)/polyaniline nanofiber modified montmorillonite nanocomposites.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Pramanik, Sujata Bharali, Pranjal Konwar, B. K. Karak, Niranjan
Description	Country affiliation: India Author Affiliation: Pramanik S ( Advanced Polymer and Nanomaterial Laboratory, Department of Chemical Sciences, Tezpur University, Tezpur 784028, India.); Bharali P ( Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784028, India.); Konwar BK ( Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784028, India.); Karak N ( Advanced Polymer and Nanomaterial Laboratory, Department of Chemical Sciences, Tezpur University, Tezpur 784028, India. Electronic address: karakniranjan@yahoo.com.)
Abstract	There has been growing interest in the use of nanomaterials featuring potent of antimicrobial activity in the biomedical domain. It still remains a challenge for the researchers to develop an efficient nanocomposite possessing antimicrobial efficacy against broad spectrum microbes including bacteria, fungi as well as algal consortium, posing serious challenges for the human survival. In addressing the above problem, we report the fabrication of bio-based hyperbranched poly(ester amide) (HBPEA)/polyaniline nanofiber modified montmorillonite (MMT) nanocomposites by an ex-situ polymerization technique at varied weight percentages (1, 2.5, 5 wt.%) of the modified MMT (nanohybrid). The Fourier transform infrared spectroscopy confirmed the structural changes upon interaction of the nanohybrid with HBPEA. A probable mechanism is proposed for the formation of nanocomposites with partially exfoliated nanoplatelet structure, which was further confirmed from the high resolution transmission electron microscopic analyses. The prepared nanocomposites exhibited potent efficacy against gram positive bacteria like Bacillus subtilis and Staphylococcus aureus as compared to the gram negative ones like Pseudomonas aeruginosa and Escherichia coli. The nanocomposites showed significant antifungal activity against Aspergillus niger, Fusarium oxysporum and Coleotricum capcii and antialgal activity against algal consortium comprising of Chlorella, Hormidium and Cladophorella species. The formation of thermosetting nanocomposites resulted in the acceptable improvement of desired physico-chemical and mechanical properties including thermostability. Thus pronounced antimicrobial activity of the nanocomposites against a spectrum of bacterial and fungal strains as well as a consortium of algal species along with other desired performance vouched them as potent antimicrobial materials in the realm of health and biomedical industry.
File Format	HTM / HTML
ISSN	09284931
Volume Number	35
e-ISSN	18730191
Journal	Materials Science and Engineering: C
Language	English
Publisher	Elsevier
Publisher Date	2014-02-01
Publisher Place	Netherlands
Access Restriction	Subscribed
Subject Keyword	Discipline Materials Science Aniline Compounds Chemistry Pharmacology Bacterial Physiological Phenomena Drug Effects Bentonite Fungi Nanocomposites Administration & Dosage Polyamines Polyesters Anti-infective Agents Chemical Synthesis Cell Survival Physiology Hardness Materials Testing Ultrastructure Nanofibers Tensile Strength Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Mechanics of Materials Biomaterials Condensed Matter Physics Bioengineering Mechanical Engineering

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