NDLI: Current status of intestinal transplantation in Japan.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ueno, T. Wada, M. Hoshino, K. Yonekawa, Y. Fukuzawa, M.
Spatial Coverage	Japan
Description	Country affiliation: Japan Author Affiliation: Ueno T ( Pediatric Surgery, Osaka University, Osaka, Japan. ueno@pedsurg.med.osaka-u.ac.jp)
Abstract	The development of total parenteral nutrition (TPN) has dramatically improved the prognosis of patients afflicted with intestinal failure. However, TPN-related complications, which remain a problem for patients with intestinal failure can be addressed by intestinal transplantation, which can significantly improve their prognosis and quality of life. The first intestinal transplantation in Japan occurred in 1996. Of the 17 intestinal transplantations performed to date, six were obtained from deceased donors and 11 from living donors. The primary indications were: short gut syndrome (n = 8), intestinal function disorder (n = 7), and retransplantation (n = 2). In our experience, the 1-year and 5-year patient survival rates are 87% and 69%. All nine patients receiving transplants in the last 7 years have survived, which seem to be acceptable results for the treatment of intestinal failure. Relatively few intestinal transplantations have been performed to date, mainly due to the lack of national health insurance coverage for the procedure and the ban of the use of donors below 15 years of age. Liver failure patients are also ineligible because liver-intestine or multiorgan transplants are not allowed by current guidelines. Case numbers may increase in the future as the result of allowing for pediatric donors in the new Act on Organ Transplantation, which went into effect in July 2010. We continue to work on reforming national insurance coverage to cover multiorgan transplantations.
File Format	HTM / HTML
ISSN	00411345
Issue Number	6
Volume Number	43
e-ISSN	18732623
Journal	Transplantation Proceedings
Language	English
Publisher	Elsevier
Publisher Date	2011-07-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Transplantation__semicolon__medicine Intestinal Diseases Surgery Intestines Transplantation Organ Transplantation Adolescent Child Child, Preschool Female Humans Infant Infant, Newborn Japan Male Adverse Effects Mortality Parenteral Nutrition, Total Reoperation Short Bowel Syndrome Survival Rate Time Factors Treatment Outcome Young Adult Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Transplantation Surgery

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